Sr Scientist
Amgen
2 hours ago
On-site
Thousand Oaks, CA
Clinical Research and Development
Sr Scientist (Mass Spectrometry–Based Proteomics) — Thousand Oaks, CA
Responsibilities:
- Design, develop, and optimize high-throughput mass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery
- Execute automated sample preparation and LC-MS/MS analysis across a broad range of high-throughput proteomics assays
- Collaborate closely with chemistry, biology, and disease area teams as a technical and scientific subject matter expert for data-driven decision-making
- Perform data analysis and generate insights into mechanism of action, target engagement, and selectivity using proteomics approaches
- Present research findings at internal and external meetings and communicate plans, results, and analyses to cross-functional teams
- Maintain accurate and organized documentation of experiments, protocols, and analyses
Basic Qualifications:
- Doctorate degree (PhD, PharmD, or MD) with relevant experience OR
- Master’s degree and 4 years of directly related experience OR
- Bachelor’s degree and 6 years of directly related experience
Preferred Qualifications:
- Doctorate degree in proteomics, chemoproteomics, biochemistry, chemistry, or a related discipline
- Strong track record developing mass spectrometry–based proteomics assays, operating advanced platforms (e.g., Orbitrap Astral), and analyzing proteomics data
- Experience with sample preparation miniaturization and automation platforms
- 3+ years of experience in biotech or pharmaceutical industry
- Demonstrated innovation in assay, method, or platform development
- Strong quantitative and computational expertise in high-dimensional proteomics data analysis
- Ability to work effectively in a highly integrated, collaborative team environment with excellent organizational and communication skills and reliable/reproducible results
- Knowledge of targeted protein degradation or E3 ligase biology (plus)
Benefits (explicitly stated):
- Retirement and Savings Plan, group medical/dental/vision, life and disability insurance, flexible spending accounts
- Discretionary annual bonus (or field sales incentive plan)
- Stock-based long-term incentives
- Time-off plans
- Flexible work models where possible
Application Instructions:
- Apply at careers.amgen.com.
- No application deadline; applications are accepted until a sufficient number of candidates are received or a candidate is selected.
Responsibilities:
- Design, develop, and optimize high-throughput mass spectrometry–based proteomics workflows and screening platforms to accelerate drug discovery
- Execute automated sample preparation and LC-MS/MS analysis across a broad range of high-throughput proteomics assays
- Collaborate closely with chemistry, biology, and disease area teams as a technical and scientific subject matter expert for data-driven decision-making
- Perform data analysis and generate insights into mechanism of action, target engagement, and selectivity using proteomics approaches
- Present research findings at internal and external meetings and communicate plans, results, and analyses to cross-functional teams
- Maintain accurate and organized documentation of experiments, protocols, and analyses
Basic Qualifications:
- Doctorate degree (PhD, PharmD, or MD) with relevant experience OR
- Master’s degree and 4 years of directly related experience OR
- Bachelor’s degree and 6 years of directly related experience
Preferred Qualifications:
- Doctorate degree in proteomics, chemoproteomics, biochemistry, chemistry, or a related discipline
- Strong track record developing mass spectrometry–based proteomics assays, operating advanced platforms (e.g., Orbitrap Astral), and analyzing proteomics data
- Experience with sample preparation miniaturization and automation platforms
- 3+ years of experience in biotech or pharmaceutical industry
- Demonstrated innovation in assay, method, or platform development
- Strong quantitative and computational expertise in high-dimensional proteomics data analysis
- Ability to work effectively in a highly integrated, collaborative team environment with excellent organizational and communication skills and reliable/reproducible results
- Knowledge of targeted protein degradation or E3 ligase biology (plus)
Benefits (explicitly stated):
- Retirement and Savings Plan, group medical/dental/vision, life and disability insurance, flexible spending accounts
- Discretionary annual bonus (or field sales incentive plan)
- Stock-based long-term incentives
- Time-off plans
- Flexible work models where possible
Application Instructions:
- Apply at careers.amgen.com.
- No application deadline; applications are accepted until a sufficient number of candidates are received or a candidate is selected.