Sr. Research Associate, Drug Product Development
Crinetics Pharmaceuticals
June 27, 2026
On-site
San Diego, CA
Clinical Research and Development
Position Summary
The Senior Research Associate, Drug Product Development, will support drug product formulation development from early preclinical enabling studies through clinical supply for First-in-Human (FIH) trials. Hands-on lab execution, data analysis, and technical documentation for oral and/or parenteral dosage forms. Works with formulation, analytical, DMPK, toxicology, and manufacturing teams.
Essential Job Functions And Responsibilities
- Perform hands-on formulation development for preclinical and early clinical drug products, including FIH studies.
- Prepare and evaluate formulations for in vivo (PK, tox) and clinical use.
- Execute experiments including formulation preparation, characterization, and stability testing.
- Maintain accurate experimental records in electronic laboratory notebooks (ELNs).
- Support scale-up, tech transfer, and manufacturing activities for clinical supplies.
- Assist in preparation of protocols, reports, and CMC documentation for regulatory submissions.
- Collaborate cross-functionally with analytical, DMPK, toxicology, quality, and external partners/CDMOs.
- Troubleshoot formulation/manufacturing challenges; propose solutions.
- Ensure compliance with internal procedures and applicable GMP/GxP requirements as needed.
Education And Experience
- Bachelor’s or Master’s in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related field.
- 3–5 years formulation development experience with hands-on lab experience.
- Preclinical and/or clinical formulation development experience, ideally through FIH.
Skills/Qualifications
- Oral and/or parenteral formulation experience; knowledge of common techniques/excipients.
- Strong organization, attention to detail, lab execution, and problem-solving.
- Ability to work with minimal supervision; strong communication and presentation.
- Ability to author/review development reports; collaborate cross-functionally; manage multiple priorities.
Additional
- Biology/chemical lab environment experience; EHS requirements apply.
- Travel up to 5%.
Benefits/Compensation (as stated)
- Salary range: $82,000–$103,000.
- Total rewards may include discretionary annual target bonus, stock options, ESPP, 401k match, health insurance, 20 PTO days, 10 paid holidays, and winter shutdown.
The Senior Research Associate, Drug Product Development, will support drug product formulation development from early preclinical enabling studies through clinical supply for First-in-Human (FIH) trials. Hands-on lab execution, data analysis, and technical documentation for oral and/or parenteral dosage forms. Works with formulation, analytical, DMPK, toxicology, and manufacturing teams.
Essential Job Functions And Responsibilities
- Perform hands-on formulation development for preclinical and early clinical drug products, including FIH studies.
- Prepare and evaluate formulations for in vivo (PK, tox) and clinical use.
- Execute experiments including formulation preparation, characterization, and stability testing.
- Maintain accurate experimental records in electronic laboratory notebooks (ELNs).
- Support scale-up, tech transfer, and manufacturing activities for clinical supplies.
- Assist in preparation of protocols, reports, and CMC documentation for regulatory submissions.
- Collaborate cross-functionally with analytical, DMPK, toxicology, quality, and external partners/CDMOs.
- Troubleshoot formulation/manufacturing challenges; propose solutions.
- Ensure compliance with internal procedures and applicable GMP/GxP requirements as needed.
Education And Experience
- Bachelor’s or Master’s in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related field.
- 3–5 years formulation development experience with hands-on lab experience.
- Preclinical and/or clinical formulation development experience, ideally through FIH.
Skills/Qualifications
- Oral and/or parenteral formulation experience; knowledge of common techniques/excipients.
- Strong organization, attention to detail, lab execution, and problem-solving.
- Ability to work with minimal supervision; strong communication and presentation.
- Ability to author/review development reports; collaborate cross-functionally; manage multiple priorities.
Additional
- Biology/chemical lab environment experience; EHS requirements apply.
- Travel up to 5%.
Benefits/Compensation (as stated)
- Salary range: $82,000–$103,000.
- Total rewards may include discretionary annual target bonus, stock options, ESPP, 401k match, health insurance, 20 PTO days, 10 paid holidays, and winter shutdown.