Sr. Process Engineer
Eli Lilly and Company
August 20, 2026
On-site
Indianapolis, IN
Operations
This position is an engineering role within the Process Engineering group in the Bioprocess Clinical Trials Manufacturing Facility, supporting the manufacture of bulk drug substance (API). Provides engineering support to maintenance and operations to maintain API production for development and clinical trial purposes. Key interface between development and operations during technology transfer; primary contact for equipment troubleshooting and performance issues.
Key Responsibilities:
- Monitor equipment and process performance to proactively identify production risks and optimization opportunities.
- Provide engineering/equipment input for technical transfer of new processes from development to manufacturing.
- Identify, lead, and implement continuous improvement initiatives for equipment performance, reliability, and process capability.
- Maintain working knowledge of manufacturing processes, equipment, facilities, computer systems, and operational practices.
- Lead multi-disciplinary projects to define scope, agree to design, and execute project implementation.
- Serve as primary resource for safety issues and lead equipment investigations with corrective/preventative actions.
- Ensure equipment remains qualified through lifecycle monitoring, maintenance, and documentation.
- Serve as primary point of contact for new consumables or consumable changes.
- Lead/support equipment commissioning and qualification; act as user representative for capital projects.
- Develop training materials/tools; support preventive maintenance and spare part strategy development.
- Ensure ongoing compliance with applicable HSE and Quality requirements.
Minimum Requirements:
- B.S. in engineering (Chemical, Biomedical, or Mechanical preferred)
- 3+ years supporting GMP operations in a manufacturing environment
Additional Skills/Preferences:
- Change management, deviation management, commissioning/qualification, and/or routine data monitoring
- Root cause analysis
- Pharmaceutical experience
- Industrial computer systems familiarity (e.g., UNICORN, DeltaV, OSI PI)
Additional Information:
- Monday–Friday, 8-hour days; occasional off-hours support; Travel: 0–10%
- Full-time U.S. work authorization required; employer will not sponsor work authorization/visas.
Benefits/Pay (as stated): anticipated wage $66,000–$171,600; eligibility for company bonus and comprehensive benefits including 401(k), medical/dental/vision, life insurance, time off/leave, and well-being benefits.
Key Responsibilities:
- Monitor equipment and process performance to proactively identify production risks and optimization opportunities.
- Provide engineering/equipment input for technical transfer of new processes from development to manufacturing.
- Identify, lead, and implement continuous improvement initiatives for equipment performance, reliability, and process capability.
- Maintain working knowledge of manufacturing processes, equipment, facilities, computer systems, and operational practices.
- Lead multi-disciplinary projects to define scope, agree to design, and execute project implementation.
- Serve as primary resource for safety issues and lead equipment investigations with corrective/preventative actions.
- Ensure equipment remains qualified through lifecycle monitoring, maintenance, and documentation.
- Serve as primary point of contact for new consumables or consumable changes.
- Lead/support equipment commissioning and qualification; act as user representative for capital projects.
- Develop training materials/tools; support preventive maintenance and spare part strategy development.
- Ensure ongoing compliance with applicable HSE and Quality requirements.
Minimum Requirements:
- B.S. in engineering (Chemical, Biomedical, or Mechanical preferred)
- 3+ years supporting GMP operations in a manufacturing environment
Additional Skills/Preferences:
- Change management, deviation management, commissioning/qualification, and/or routine data monitoring
- Root cause analysis
- Pharmaceutical experience
- Industrial computer systems familiarity (e.g., UNICORN, DeltaV, OSI PI)
Additional Information:
- Monday–Friday, 8-hour days; occasional off-hours support; Travel: 0–10%
- Full-time U.S. work authorization required; employer will not sponsor work authorization/visas.
Benefits/Pay (as stated): anticipated wage $66,000–$171,600; eligibility for company bonus and comprehensive benefits including 401(k), medical/dental/vision, life insurance, time off/leave, and well-being benefits.