Sr. Principal Scientist, Clinical Pharmacology

Role: Lead Clinical Pharmacology support for multiple development programs, focusing on dose selection, study design, and pharmacokinetic/pharmacodynamic analysis across diverse therapeutic modalities. Responsibilities: develop and execute clinical pharmacology strategies; lead PK/PD activities; serve as scientific representative on cross-functional teams; oversee analysis plans, reports, and regulatory documents; apply modeling and simulation for decision-making; manage external vendors and ensure compliance; communicate results; mentor junior staff; stay current with industry standards. Requirements: PhD, PharmD, or master's with 5-10+ years of relevant experience; extensive knowledge of PK/PD data interpretation; experience in managing CROs; proven record of preparing regulatory submissions; strong in modeling/simulation and regulatory guidance. HighValue: supports neuro, psychiatric, endocrine, and immunological programs; involved in clinical phases with a focus on dose and exposure-response; may contribute to INDs, NDAs, and regulatory interactions. WorkSetup: details not specified.