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Sr Manager Business Performance & Digital Enablement - Remote

Amgen
September 02, 2026
Remote friendly (United States)
United States
IT
Sr Manager Business Performance & Digital Enablement

What You Will Do
- Translate Global AUEG Portfolio Strategy, Governance, and Process into execution-ready, scalable digital operating models using technology including AI.
- Integrate and liaison between AUEG Capability and internal DTI, AI&Data teams, and external partners.
- Lead build/delivery of the cross-functional, matrixed AUEG technology platform (AUGment) to enable prioritization, governance, execution, and management of global/regional/local AUEG activities.
- Deliver the AUEG capability evolution enhancement roadmap and demonstrate realized impact.
- Strengthen organizational performance across a highly matrixed environment; drive adoption of technology-enabled capabilities and measurable business outcomes.

Key Responsibilities
Business Strategy & Capability Development
- Translate AUEG strategy/roadmap into scalable operating models and business processes with CORE/FAIR data solutions.
- Manage governance, performance measures, and operating standards for consistent execution.
- Continuously evolve AUEG capabilities; drive improvement across people, processes, technology, and data.

AUGment Business Ownership & Digital Enablement
- Partner with DTI/AI&Data product managers and solution architects; serve as business owner.
- Oversee AUGment enhancement roadmap; lead requirements, process design, UAT, deployment, and adoption.
- Identify/lead AI, automation, and emerging tech opportunities.
- Oversee collaboration and knowledge management solutions.

Data Strategy & Business Insights
- Define AUEG data strategy/roadmap and reporting framework.
- Improve data quality/governance; establish KPIs and dashboards.
- Deliver portfolio insights; advance AI-ready data foundations.

Strategic Partnerships, Adoption & People Leadership
- Primary business partner to DTI and MD&A; build trusted partnerships.
- Translate needs into prioritized capabilities/roadmap/investments.
- Lead stakeholder engagement, communication, training, and adoption.
- Identify risks and implement mitigation.
- Lead matrixed team for operational support, reporting, platform administration, and services; coach and develop team.

What We Expect of You
Basic Qualifications:
- Doctorate + 2 years, OR Master’s + 6 years, OR Bachelor’s + 8 years, OR Associate’s + 10 years, OR High school/GED + 12 years of business performance and digital enablement experience.
- Plus minimum 2 years directly managing people and/or leading teams/projects/programs/resource allocation.

Preferred Qualifications:
- Advanced degree (Business, Life Sciences, Computer Science, Engineering, or related).
- 8+ years in pharma/biotech/healthcare for business operations, digital/business capability enablement, technology implementation, or transformation.
- Experience as business/platform owner for enterprise tech platforms.
- Success evolving technology-enabled capabilities; integrate business/tech/data/AI for outcomes.
- Understanding of Medical Affairs, evidence generation, drug development, commercialization, healthcare ecosystem.
- Cross-functional leadership in matrixed organizations; manage budgets/vendors/partners.
- Knowledge of GxP, SOPs, regulatory requirements, validated processes.
- Drive adoption and continuous improvement of technology-enabled capabilities.

Benefits (if part of job description)
- Retirement and Savings Plan, health/dental/vision, life/disability, flexible spending accounts; discretionary annual bonus (or sales incentive); stock-based long-term incentives; time-off and shutdowns; flexible remote/hybrid work where possible.

Application Instructions
- Apply via careers.amgen.com. No application deadline; applications accepted until sufficient number or candidate selection.