Sr. Manager, Biostatistician / Programmer
Legend Biotech
June 28, 2026
Remote friendly (Somerset, NJ)
United States
Clinical Research and Development
Role Overview:
The Sr. Manager, Biostatistician/Programmer plays a critical hands-on role in supporting clinical development programs by transforming clinical trial data into high-quality analyses, tables, figures, and listings that inform decision-making. Partners with clinical, translational, and research stakeholders to deliver timely insights and conduct exploratory and ad hoc analyses.
Key Responsibilities:
- Develop, validate, and maintain high-quality Tables, Figures, and Listings (TFLs) for clinical trials, interim analyses, and deliverables.
- Perform hands-on statistical programming and data manipulation for planned and ad hoc analyses.
- Independently explore and interrogate clinical trial data to identify trends, anomalies, and insights.
- Collaborate with Biostatistics, Clinical Development, Clinical Operations, Data Management, Translational research, and Medical teams.
- Apply therapeutic area/disease biology/endpoints knowledge to translate data into scientific insights.
- Contribute to analysis datasets, program specifications, programming documentation, and quality control per internal/regulatory standards.
- Support process improvement (efficiency, standardization, reproducibility).
Requirements:
- Master’s degree or PhD in Statistics, Biostatistics, Mathematics, Data Science, or related quantitative discipline.
- Hands-on experience developing TFLs and ad hoc/exploratory clinical trial analyses.
- Strong understanding of clinical trial design, data structures, and medical context.
- Proven independent work ability in ambiguity.
- Advanced SAS proficiency for clinical trial analysis/reporting.
- Working knowledge of R for exploratory analyses/visualization.
- Strong experience with clinical data standards (SDTM, ADaM).
- Experience with/on strong willingness to leverage AI-assisted programming tools.
- Experience in oncology and/or cell therapy is strongly preferred.
Benefits:
- Benefits are offered exclusively to permanent full-time employees; contractors are not eligible for benefits.
The Sr. Manager, Biostatistician/Programmer plays a critical hands-on role in supporting clinical development programs by transforming clinical trial data into high-quality analyses, tables, figures, and listings that inform decision-making. Partners with clinical, translational, and research stakeholders to deliver timely insights and conduct exploratory and ad hoc analyses.
Key Responsibilities:
- Develop, validate, and maintain high-quality Tables, Figures, and Listings (TFLs) for clinical trials, interim analyses, and deliverables.
- Perform hands-on statistical programming and data manipulation for planned and ad hoc analyses.
- Independently explore and interrogate clinical trial data to identify trends, anomalies, and insights.
- Collaborate with Biostatistics, Clinical Development, Clinical Operations, Data Management, Translational research, and Medical teams.
- Apply therapeutic area/disease biology/endpoints knowledge to translate data into scientific insights.
- Contribute to analysis datasets, program specifications, programming documentation, and quality control per internal/regulatory standards.
- Support process improvement (efficiency, standardization, reproducibility).
Requirements:
- Master’s degree or PhD in Statistics, Biostatistics, Mathematics, Data Science, or related quantitative discipline.
- Hands-on experience developing TFLs and ad hoc/exploratory clinical trial analyses.
- Strong understanding of clinical trial design, data structures, and medical context.
- Proven independent work ability in ambiguity.
- Advanced SAS proficiency for clinical trial analysis/reporting.
- Working knowledge of R for exploratory analyses/visualization.
- Strong experience with clinical data standards (SDTM, ADaM).
- Experience with/on strong willingness to leverage AI-assisted programming tools.
- Experience in oncology and/or cell therapy is strongly preferred.
Benefits:
- Benefits are offered exclusively to permanent full-time employees; contractors are not eligible for benefits.