Sr. Manager, Biostatistician / Programmer
Legend Biotech
August 11, 2026
On-site
Somerset, NJ
Clinical Research and Development
Role Overview
- Sr. Manager, Biostatistician/Programmer supports clinical development by transforming clinical trial data into high-quality analyses, tables, figures, and listings that inform decision-making.
- Partners with clinical, translational, and research stakeholders to deliver timely insights and conduct exploratory and ad hoc analyses.
Key Responsibilities
- Develop, validate, and maintain high-quality Tables, Figures, and Listings (TFLs) for clinical trials, interim analyses, and internal/external deliverables.
- Perform hands-on statistical programming and data manipulation for planned and ad hoc analyses.
- Independently explore and interrogate clinical trial data to identify trends, anomalies, and insights.
- Collaborate with Biostatistics, Clinical Development, Clinical Operations, Data Management, Translational research, and Medical teams.
- Translate understanding of therapeutic area, disease biology, and clinical endpoints into scientific insights.
- Contribute to analysis datasets, program specifications, documentation, and quality control.
- Support process improvement (efficiency, standardization, reproducibility).
- Use autonomy to determine programming approaches and investigative strategies; escalate for changes affecting strategy, major deliverables, timelines, or regulatory-facing outputs.
Requirements
- Master’s or PhD in Statistics, Biostatistics, Mathematics, Data Science, or related quantitative discipline.
- Hands-on experience developing TFLs and ad hoc/exploratory clinical trial analyses.
- Strong understanding of clinical trial design and medical context.
- Ability to work independently, manage ambiguity, and drive self-directed discovery.
- Strong oncology and/or cell therapy experience preferred.
- Advanced SAS proficiency for clinical trial analysis/reporting.
- Working knowledge of R for exploratory analyses and visualization.
- Strong experience with clinical data standards (SDTM, ADaM).
- Experience with or willingness to use AI-assisted programming tools.
Benefits
- Benefits are offered exclusively to permanent full-time employees (contractors not eligible for benefits).
- Sr. Manager, Biostatistician/Programmer supports clinical development by transforming clinical trial data into high-quality analyses, tables, figures, and listings that inform decision-making.
- Partners with clinical, translational, and research stakeholders to deliver timely insights and conduct exploratory and ad hoc analyses.
Key Responsibilities
- Develop, validate, and maintain high-quality Tables, Figures, and Listings (TFLs) for clinical trials, interim analyses, and internal/external deliverables.
- Perform hands-on statistical programming and data manipulation for planned and ad hoc analyses.
- Independently explore and interrogate clinical trial data to identify trends, anomalies, and insights.
- Collaborate with Biostatistics, Clinical Development, Clinical Operations, Data Management, Translational research, and Medical teams.
- Translate understanding of therapeutic area, disease biology, and clinical endpoints into scientific insights.
- Contribute to analysis datasets, program specifications, documentation, and quality control.
- Support process improvement (efficiency, standardization, reproducibility).
- Use autonomy to determine programming approaches and investigative strategies; escalate for changes affecting strategy, major deliverables, timelines, or regulatory-facing outputs.
Requirements
- Master’s or PhD in Statistics, Biostatistics, Mathematics, Data Science, or related quantitative discipline.
- Hands-on experience developing TFLs and ad hoc/exploratory clinical trial analyses.
- Strong understanding of clinical trial design and medical context.
- Ability to work independently, manage ambiguity, and drive self-directed discovery.
- Strong oncology and/or cell therapy experience preferred.
- Advanced SAS proficiency for clinical trial analysis/reporting.
- Working knowledge of R for exploratory analyses and visualization.
- Strong experience with clinical data standards (SDTM, ADaM).
- Experience with or willingness to use AI-assisted programming tools.
Benefits
- Benefits are offered exclusively to permanent full-time employees (contractors not eligible for benefits).