Sr. Manager/Associate Director, Quantitative Science

Role Summary

The Quantitative Science team at BioMarin performs statistics and data science across research and development and beyond. As the Senior Manager or Associate Director of Quantitative Science, you will assume the role of a statistician/data scientist and play a pivotal role in supporting different functional areas. This influential and self-sufficient position will make significant contributions to drug discovery, nonclinical research, preclinical research, experimental medicine, biomarker development, clinical development, post-approval/medical areas, real-world data/real-world evidence (RWD/RWE), genomics, business development, and manufacturing. Your primary responsibility will be to ensure excellence in the design, analysis, interpretation, and communication of data. Additionally, you will actively engage with counterparts to foster collaboration and champion the use of quantitative thinking.

Responsibilities

• Perform statistical experimental design, analysis, interpretation, and reporting, including for example
• Estimate sample size and aid in study design including conducting simulations
• Conceptualize solutions to unique challenges and develop analysis methods and analysis programs accordingly
• Explore and develop the use of artificial intelligence (AI) and machine learning (ML)
• Write statistical analysis reports and give presentations
• Develop statistical applications that enable researchers to analyze repetitive experiments
• Conduct outreach to internal functions, establishing collaborations and providing education to identify opportunities to apply statistics and data science that positively impact the business
• Provide guidance and direction to junior staff on the team

Education & Experience

• M.S. in Biostatistics, Statistics, Data Science, or similar field required. Ph.D. in Biostatistics, Statistics, Data Science, or similar field preferred.
• Minimum Qualifications: Years of experience in pharmaceutical and/or biotech industry: A minimum of 5 (PhD) or 7 (Master’s) for associate director; A minimum of 2 (PhD) or 4 (Master’s) for senior manager.

Preferred Qualifications

• Overall:
  • Basic broad knowledge of the research, development, and associated areas in the pharmaceutical/biotechnology field
  • Broad knowledge of statistical methods and ability to solve problems creatively and pragmatically
  • Scientific curiosity and ability to learn
  • Exceptional consultative, conversational, written communication, presenting, collaborative, teaching, and interpersonal skills
  • Adaptability and ability to thrive in a dynamic, diverse, and matrixed environment

Skills

• Hands-on knowledge of statistical methods applicable across research and development such as time-to-event analyses, analysis of covariance, mixed models for repeated measures, categorical data approaches, Bayesian methods, simulation approaches, AI/ML, graphical methods, etc.
• Hands-on knowledge of study design and sample size calculation
• Strong programming skills in at least two of SAS, R, or Python

Additional Requirements

• Proficiency in or demonstrated ability to learn developing specifications and designing analysis modules to automate analysis, visualization, and reporting of standardized experiments; proficiency in documenting and supporting such systems
• Demonstrated ability to lead, motivate, and mentor both internal and contract staff
• Effective review and evaluation skills for documents drafted by staff