Sr. Director, US Team Lead Sigvotatug Vedotin

Role Summary

At Pfizer Oncology, our purpose is to Outdo Cancer by delivering transformative medicines that have the potential to meaningfully change outcomes for patients. Pfizer Oncology’s industry-leading pipeline spans breast, genitourinary (GU), hematology, gastroenterology, and thoracic therapeutic areas, reflecting both scientific depth and sustained investment in areas of high unmet need. The US Precision Medicine/Thoracic Franchise is positioned for significant growth, supported by a differentiated thoracic portfolio that includes Sigvotatug Vedotin (SGN‑B6A / IB6), an investigational antibody-drug conjugate (ADC) under development for the treatment of non-small cell lung cancer (NSCLC). Sigvotatug Vedotin represents a potential next-generation approach within thoracic oncology, reinforcing Pfizer’s commitment to advancing precision-based strategies and expanding therapeutic options in a highly competitive and evolving landscape. This asset, alongside a strong future thoracic pipeline, underscores the franchise’s long-term strategic importance to Pfizer Oncology. The role is ideally suited for an experienced, enterprise-minded leader with deep US commercial marketing expertise and a strong track record of operating at scale. The successful candidate will lead and develop a high-performing team of marketers while partnering closely with Global Marketing, Medical, Market Access, and the broader US Precision Medicine/Lung portfolio team to deliver a fully integrated, insight-driven go-to-market strategy that advances patient outcomes and drives sustainable franchise growth. Locations: New York, NY; Collegeville, PA; Cambridge, MA; Bothell, WA; Lake Forest, IL.

Responsibilities

• Provide direct leadership and mentorship to a team of director and senior manager-level marketers, cultivating a high-performance culture and unlocking the full potential of the brand.
• Take comprehensive responsibility for all U.S. pre-launch and launch initiatives for Sigvotatug Vedotin, ensuring thorough preparation and seamless execution.
• Shape and implement the U.S. go-to-market strategy collaboratively, working closely with Global Marketing and Market Access teams to optimize impact.
• Guide the co-development of best-in-class launch materials for healthcare professionals (HCPs) with Global Marketing, ensuring Sigvotatug Vedotin is optimally positioned for success amid competitive dynamics.
• Identify, assess, and execute strategic growth opportunities for the brand through detailed planning and data-informed decisions.
• Lead the creation and delivery of annual strategic and tactical plans designed to support both immediate and long-term HCP and patient objectives, grounded in key customer insights.
• Continuously measure and enhance the effectiveness of HCP marketing activities, generating actionable insights to fuel ongoing brand improvement.
• Oversee all processes related to the brand’s annual operating plan and latest estimates, maintaining strong alignment with overall business objectives.
• Collaborate with Medical, Market Analytics, Field Force, and prescribers to extract essential customer insights and translate them into robust commercial strategies.
• Manage the brand’s advertising and promotion (A&P) budget and direct agency partnerships to guarantee operational excellence and financial stewardship.

Qualifications

• Required: Educational Background: Bachelor’s degree with at least 12+ years of progressive pharmaceutical industry experience, or a Master’s degree with a minimum of 10+ years’ experience, or a Ph.D./PharmD with at least 7+ years of relevant experience.
• Required: Leadership Experience: Minimum of 5 years leading and managing marketing teams across all levels, from Manager to Director. Proven commitment to fostering team engagement, cultivating a positive and collaborative culture, and mentoring and developing talent.
• Required: Product Launch Expertise: Demonstrated track record of success in U.S. product launches and lifecycle management. Prior experience with both U.S. and/or global product launches and lifecycle strategies is highly valued.
• Required: Cross-Functional Collaboration: Extensive experience collaborating and interfacing with field sales, medical affairs, regulatory, and supply chain teams, ensuring seamless execution across all stages of the product lifecycle.
• Required: Strategic and Analytical Skills: Outstanding strategic thinking and problem-solving abilities, including the capacity to evaluate complex business opportunities, make informed trade-off decisions, and build compelling business cases to drive growth.
• Required: Stakeholder Management: Ability to work autonomously and effectively engage senior-level stakeholders, exercising sound judgment on escalation and ensuring strong alignment with organizational objectives.
• Required: Communication and Presentation: Superior oral and written communication skills with a proven ability to deliver clear, persuasive presentations and influence diverse audiences.
• Required: Project and Team Leadership: Exceptional project management capabilities with a history of successfully leading large, diverse, cross-functional teams to deliver results on multiple, high-priority initiatives in fast-paced, deadline-driven settings.
• Required: Leadership Impact: Demonstrates a breadth of diverse leadership experience, including influencing and collaborating with peers, coaching and developing others, and effectively overseeing and guiding the work of colleagues to achieve meaningful business outcomes.
• Required: Results Orientation: Proven ability to manage and deliver on multiple, complex, and competing projects simultaneously. Highly self-motivated, driven by achieving results, and adept at organizing and prioritizing numerous projects over time.
• Preferred: MBA or other advanced degrees are desirable
• Preferred: Previous US Marketing experience preferred.
• Preferred: Oncology experience preferred but not required.

Additional Requirements

• Ability to travel domestically and internationally as needed for congresses and customer engagements. Expected domestic travel 20%.