Sr. Director, Process Chemistry

Role: Lead synthetic molecule route commercialization and process optimization for drug candidates supporting clinical trials, commercialization, and regulatory submissions. Responsibilities: design and develop new synthetic routes for APIs using modern technologies; oversee process scale-up, transfer, and validation; lead cross-disciplinary teams including chemists and engineers; collaborate with external R&D and CMO partners; evaluate and incorporate new manufacturing technologies; ensure processes meet regulatory standards and facilitate documentation for submissions. Requirements: Ph.D. in organic chemistry or related field with 10+ years (Ph.D.) or MS with 15+ years of pharmaceutical process development experience; expertise in modern synthetic organic chemistry, unit operation design, process modeling, and tech transfer; knowledge of PAT, modeling, and data analytics; strong leadership, communication, and project management skills. Preferred: experience in active ingredient development, regulatory submissions, and an established publication record. High-Value: small molecule APIs, drug development stages from preclinical to commercialization, process scale-up, and regulatory readiness; location: Indianapolis, IN; travel: up to 10%.