Sr Director, Epidemiology and Real World Evidence Franchise Lead (Oncology)
Gilead Sciences
August 19, 2026
Remote friendly (San Francisco Bay Area)
United States
Clinical Research and Development
Position Description
The Senior Director, EpiRWE Oncology Franchise Lead in Early Development leads development and execution of an RWE strategy for one or more Oncology franchises.
Duties & Responsibilities
- Single point of accountability for global EpiRWE strategy supporting early-stage clinical development evidence needs across an Oncology franchise and its pipeline indications.
- Ensure robust scientific methods and fit-for-purpose data resources aligned to the clinical development plan and cross-functional objectives.
- Provide regulatory-facing epidemiology/RWE subject-matter expertise (EMT member; DET situational member).
- Lead proactive EpiRWE generation (e.g., natural history, population characterization, treatment patterns/unmet need, external comparators, benchmarking outcomes, comparative safety/effectiveness).
- Drive use of EpiRWE results across internal/external decisions; communicate observational research outcomes (regulatory document sections, publications, white papers, press releases).
- Oversee epidemiology sections for regulatory documents globally (e.g., RMP, orphan/breakthrough designations, Pediatric Investigation Plan, query responses, advisory briefing documents).
- Represent EpiRWE in cross-functional initiatives and external organizations (associations, societies, regulatory working groups).
- Collaborate with quantitative functions (Biostatistics, Bioinformatics, Clinical Pharmacology) and teams across Research, Clinical Research, Medical Affairs, and Global Value & Access.
- Identify process/training gaps to improve efficiency, quality, and impact.
Requirements
- Doctoral (PhD/MD/ScD/PharmD) and/or Master’s (MSc) in Epidemiology or related field; minimum 12 years relevant post-graduation experience (preferred 6+ in biopharmaceutical industry).
- Publication track record in observational study design/analysis/interpretation; direct experience with Epidemiology/RWE for early-stage development and regulatory approvals.
- Demonstrated oncology therapeutic area understanding (disease, treatment practice/guidelines, trial endpoints, safety outcomes).
- Ability to work autonomously, collaborate cross-functionally, manage priorities/resources in changing environments, and communicate proactively.
- Cross-cultural sensitivity.
Compensation/Benefits (as stated)
- Salary range: Bay Area $261,375–$338,250; Other US Locations $237,575–$307,450; may include discretionary bonus and long-term incentives; paid time off and medical/dental/vision/life insurance.
Application Instructions
- For current employees/contractors: apply via the Internal Career Opportunities portal in Workday.
The Senior Director, EpiRWE Oncology Franchise Lead in Early Development leads development and execution of an RWE strategy for one or more Oncology franchises.
Duties & Responsibilities
- Single point of accountability for global EpiRWE strategy supporting early-stage clinical development evidence needs across an Oncology franchise and its pipeline indications.
- Ensure robust scientific methods and fit-for-purpose data resources aligned to the clinical development plan and cross-functional objectives.
- Provide regulatory-facing epidemiology/RWE subject-matter expertise (EMT member; DET situational member).
- Lead proactive EpiRWE generation (e.g., natural history, population characterization, treatment patterns/unmet need, external comparators, benchmarking outcomes, comparative safety/effectiveness).
- Drive use of EpiRWE results across internal/external decisions; communicate observational research outcomes (regulatory document sections, publications, white papers, press releases).
- Oversee epidemiology sections for regulatory documents globally (e.g., RMP, orphan/breakthrough designations, Pediatric Investigation Plan, query responses, advisory briefing documents).
- Represent EpiRWE in cross-functional initiatives and external organizations (associations, societies, regulatory working groups).
- Collaborate with quantitative functions (Biostatistics, Bioinformatics, Clinical Pharmacology) and teams across Research, Clinical Research, Medical Affairs, and Global Value & Access.
- Identify process/training gaps to improve efficiency, quality, and impact.
Requirements
- Doctoral (PhD/MD/ScD/PharmD) and/or Master’s (MSc) in Epidemiology or related field; minimum 12 years relevant post-graduation experience (preferred 6+ in biopharmaceutical industry).
- Publication track record in observational study design/analysis/interpretation; direct experience with Epidemiology/RWE for early-stage development and regulatory approvals.
- Demonstrated oncology therapeutic area understanding (disease, treatment practice/guidelines, trial endpoints, safety outcomes).
- Ability to work autonomously, collaborate cross-functionally, manage priorities/resources in changing environments, and communicate proactively.
- Cross-cultural sensitivity.
Compensation/Benefits (as stated)
- Salary range: Bay Area $261,375–$338,250; Other US Locations $237,575–$307,450; may include discretionary bonus and long-term incentives; paid time off and medical/dental/vision/life insurance.
Application Instructions
- For current employees/contractors: apply via the Internal Career Opportunities portal in Workday.