Sr Director, Early Clinical Development, Neuroscience
Bristol Myers Squibb
August 13, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
Position Summary / Objective
- Serve as clinical oversight for a matrixed group of physicians in neuroscience for evaluation and clinical development planning for research pipeline assets.
- Oversee Global Clinical Physicians and manage clinical aspects of Phase 1 trials in neuroscience.
- Provide matrix leadership, develop/motivate teams, and ensure adherence to People Strategy.
- Ensure studies meet regulatory, quality, medical, and access goals.
Position Responsibilities
- Early Phase Trials: May serve as independent Medical Monitor for Phase 1 by articulating clinical development strategy; analyzing/interpreting/acting on trial data.
- Independently synthesize/contribute to plans (trial design, development strategy, regulatory strategy) based on emerging data.
- Supervise/participate in design and development of clinical studies (first-in-human Phase I, biomarker qualification, clinical pharmacology).
- Set execution priorities and partner with Global Clinical Scientists.
- Clinical Development Expertise/Strategy: Participate in clinical strategy planning for multiple complex programs; contribute to indication strategy and initial clinical development plans.
- Provide disease area expertise; partner with KOLs; liaise with Translational/Discovery and other functions for dose/indications/patient selection and translational objectives.
- Present/articulate clinical strategy to senior leadership.
- Health Authority Interactions: Primary clinical oversight in regulatory interactions.
- Leadership/Matrix Management: Supervise Phase 1 and research tasks; attract/develop/retain talent; mentor; lead by influence; ensure GCP/compliance.
Degree Requirements
- MD or MD/PhD; deep clinical expertise in neuroscience.
Experience Requirements
- 7+ years relevant discovery/translational/clinical research experience.
- Extensive clinical trial design/execution, biomarker development, and development strategy.
- Deep understanding of pharma discovery/development/commercialization; track record of mentorship/management/matrix leadership; leadership in a matrix environment.
Key Competencies
- Clinical development strategy (including clinical components of regulatory submissions).
- External focus to understand disease-area treatment trends and build relationships with external partners.
- Collaborate with Clinical Development to transition into Phase II–III trials.
Travel Required
- Domestic and international travel may be required.
Compensation / Benefits (explicit)
- Compensation range (FTE): Cambridge Crossing $350,780–$425,060; Madison/Giralda NJ $313,200–$379,524; Princeton NJ $313,200–$379,524.
- Benefits include health coverage, wellbeing support, and financial protection (e.g., 401(k), disability, life insurance).
- Serve as clinical oversight for a matrixed group of physicians in neuroscience for evaluation and clinical development planning for research pipeline assets.
- Oversee Global Clinical Physicians and manage clinical aspects of Phase 1 trials in neuroscience.
- Provide matrix leadership, develop/motivate teams, and ensure adherence to People Strategy.
- Ensure studies meet regulatory, quality, medical, and access goals.
Position Responsibilities
- Early Phase Trials: May serve as independent Medical Monitor for Phase 1 by articulating clinical development strategy; analyzing/interpreting/acting on trial data.
- Independently synthesize/contribute to plans (trial design, development strategy, regulatory strategy) based on emerging data.
- Supervise/participate in design and development of clinical studies (first-in-human Phase I, biomarker qualification, clinical pharmacology).
- Set execution priorities and partner with Global Clinical Scientists.
- Clinical Development Expertise/Strategy: Participate in clinical strategy planning for multiple complex programs; contribute to indication strategy and initial clinical development plans.
- Provide disease area expertise; partner with KOLs; liaise with Translational/Discovery and other functions for dose/indications/patient selection and translational objectives.
- Present/articulate clinical strategy to senior leadership.
- Health Authority Interactions: Primary clinical oversight in regulatory interactions.
- Leadership/Matrix Management: Supervise Phase 1 and research tasks; attract/develop/retain talent; mentor; lead by influence; ensure GCP/compliance.
Degree Requirements
- MD or MD/PhD; deep clinical expertise in neuroscience.
Experience Requirements
- 7+ years relevant discovery/translational/clinical research experience.
- Extensive clinical trial design/execution, biomarker development, and development strategy.
- Deep understanding of pharma discovery/development/commercialization; track record of mentorship/management/matrix leadership; leadership in a matrix environment.
Key Competencies
- Clinical development strategy (including clinical components of regulatory submissions).
- External focus to understand disease-area treatment trends and build relationships with external partners.
- Collaborate with Clinical Development to transition into Phase II–III trials.
Travel Required
- Domestic and international travel may be required.
Compensation / Benefits (explicit)
- Compensation range (FTE): Cambridge Crossing $350,780–$425,060; Madison/Giralda NJ $313,200–$379,524; Princeton NJ $313,200–$379,524.
- Benefits include health coverage, wellbeing support, and financial protection (e.g., 401(k), disability, life insurance).