Sr. Director, Commercial Supply Chain
Structure Therapeutics
August 18, 2026
Remote friendly (South San Francisco, CA)
United States
Operations
Position Summary:
Sr. Director, Commercial Supply Chain (reporting to VP, Global Manufacturing & Supply Chain) provides strategic and operational leadership for end-to-end supply chain planning for late-phase clinical and commercial small molecule programs, ensuring uninterrupted supply of drug substance, drug product, and packaging/labeling.
Responsibilities:
- Define and execute global supply chain strategies for clinical development, commercialization, and lifecycle management.
- Lead Sales & Operations Planning (S&OP) and Clinical Operations Planning (C&OP); align demand forecasts with manufacturing/supply capabilities.
- Lead demand/supply balancing across supply chain echelons; refine forecast accuracy.
- Define/manage inventory strategies and safety stock; monitor turns, expiry risk, and working capital; optimize for service/cost/risk.
- Lead launch supply planning (scenario planning, risk mitigation) and ensure launch readiness and regulatory/market-entry support.
- Lead long-range network planning; identify/mitigate supply risks; maintain risk frameworks; support business continuity/supply resilience.
- Select/implement planning tools; ensure master data management; support ERP implementation/integration; drive digital transformation.
- Oversee logistics/storage/distribution; ensure CRT and cold-chain compliance; coordinate with CDMOs/depots; optimize distribution networks.
- Partner cross-functionally (External Manufacturing, Quality, Regulatory, Clinical Ops, Commercial) and drive continuous improvement.
Qualifications (Required/Preferred):
- B.S. in Supply Chain/Engineering/Chemistry or related (MBA preferred).
- 15+ years in pharma/biotech supply chain; deep expertise in small molecule and oral solid dose (OSD) supply chains.
- Expertise in supply chain planning, S&OP/C&OP, inventory management, launch planning, and global outsourced/CDMO networks.
- Strong GMP/regulatory, validation/CPV, quality systems; ERP/planning systems; capacity/production planning; logistics and cold-chain.
- Demonstrated risk management and supply resilience; excellent leadership and cross-functional influence; thrives in matrix/virtual environments.
- Travel: up to 20–25% globally.
Benefits (as stated):
- Annual performance incentive bonus; new hire equity; ongoing performance-based equity; medical/dental/vision; 401k match; unlimited PTO; paid holidays including winter shutdown.
Application Instructions:
- Apply via the official career page at BambooHR.
Sr. Director, Commercial Supply Chain (reporting to VP, Global Manufacturing & Supply Chain) provides strategic and operational leadership for end-to-end supply chain planning for late-phase clinical and commercial small molecule programs, ensuring uninterrupted supply of drug substance, drug product, and packaging/labeling.
Responsibilities:
- Define and execute global supply chain strategies for clinical development, commercialization, and lifecycle management.
- Lead Sales & Operations Planning (S&OP) and Clinical Operations Planning (C&OP); align demand forecasts with manufacturing/supply capabilities.
- Lead demand/supply balancing across supply chain echelons; refine forecast accuracy.
- Define/manage inventory strategies and safety stock; monitor turns, expiry risk, and working capital; optimize for service/cost/risk.
- Lead launch supply planning (scenario planning, risk mitigation) and ensure launch readiness and regulatory/market-entry support.
- Lead long-range network planning; identify/mitigate supply risks; maintain risk frameworks; support business continuity/supply resilience.
- Select/implement planning tools; ensure master data management; support ERP implementation/integration; drive digital transformation.
- Oversee logistics/storage/distribution; ensure CRT and cold-chain compliance; coordinate with CDMOs/depots; optimize distribution networks.
- Partner cross-functionally (External Manufacturing, Quality, Regulatory, Clinical Ops, Commercial) and drive continuous improvement.
Qualifications (Required/Preferred):
- B.S. in Supply Chain/Engineering/Chemistry or related (MBA preferred).
- 15+ years in pharma/biotech supply chain; deep expertise in small molecule and oral solid dose (OSD) supply chains.
- Expertise in supply chain planning, S&OP/C&OP, inventory management, launch planning, and global outsourced/CDMO networks.
- Strong GMP/regulatory, validation/CPV, quality systems; ERP/planning systems; capacity/production planning; logistics and cold-chain.
- Demonstrated risk management and supply resilience; excellent leadership and cross-functional influence; thrives in matrix/virtual environments.
- Travel: up to 20–25% globally.
Benefits (as stated):
- Annual performance incentive bonus; new hire equity; ongoing performance-based equity; medical/dental/vision; 401k match; unlimited PTO; paid holidays including winter shutdown.
Application Instructions:
- Apply via the official career page at BambooHR.