Sr. Clinical Trials Manager
Neurocrine Biosciences
August 22, 2026
Remote friendly (San Diego, CA)
United States
Clinical Research and Development
About The Role
Contribute to overall clinical trial strategy and manage operational activities to support planning, initiation, conduct, and close-out of clinical studies. Lead end-to-end operational activities for assigned clinical studies (domestic and global). Manage studies using multiple CROs and internally run studies. Ensure integrity of clinical trial data and completeness of Trial Master File (TMF) documentation.
Your Contributions
- Develop, lead, and manage NBI trials end-to-end and contribute to trial strategy and planning
- Serve as primary clinical operations point of contact for assigned studies; may oversee lower-level team members
- Provide expert counsel on clinical trial outlines, protocols, and clinical study reports; participate/lead design discussions
- Manage CROs and other contract service providers (CSPs)
- Oversee study team meetings; manage issues and develop timelines; identify enrollment barriers and recruitment solutions
- Manage internally run studies (incl. monitoring teams); create monitoring plans, on-site monitoring guidelines/tools/forms, and conduct monitoring visits
- Implement and enforce NBI standard processes across clinical programs
- Manage TMF content to ensure documents are filed and inspection-ready
- Ensure studies comply with FDA regulations, EU Directive, ICH guidelines, and NBI SOPs/policies
- Incorporate Risk Based Monitoring with Clinical Quality Assurance to assure subject safety and data integrity
- May support recruitment, training, management, and career development of subordinates
Requirements
- BS/BA + 8+ years clinical trial management (CRO/vendor management, budget scope monitoring, site monitoring) OR Master’s + 6+ years
- Expert knowledge of clinical drug development (ICH, GCP, FDA, EU)
- Strong knowledge of clinical operations and trial startup-through-close-out
- Strong trial management protocol/process knowledge across phases
- Excellent communication/presentation and computer/organizational skills
- Ability to lead multiple teams; strong leadership/mentoring and project management
Benefits (as stated)
- Annual bonus (target 30%), retirement plan with match, paid vacation/holidays/personal days, paid caregiver/parental and medical leave, and health benefits (medical, prescription drug, dental, vision).
Contribute to overall clinical trial strategy and manage operational activities to support planning, initiation, conduct, and close-out of clinical studies. Lead end-to-end operational activities for assigned clinical studies (domestic and global). Manage studies using multiple CROs and internally run studies. Ensure integrity of clinical trial data and completeness of Trial Master File (TMF) documentation.
Your Contributions
- Develop, lead, and manage NBI trials end-to-end and contribute to trial strategy and planning
- Serve as primary clinical operations point of contact for assigned studies; may oversee lower-level team members
- Provide expert counsel on clinical trial outlines, protocols, and clinical study reports; participate/lead design discussions
- Manage CROs and other contract service providers (CSPs)
- Oversee study team meetings; manage issues and develop timelines; identify enrollment barriers and recruitment solutions
- Manage internally run studies (incl. monitoring teams); create monitoring plans, on-site monitoring guidelines/tools/forms, and conduct monitoring visits
- Implement and enforce NBI standard processes across clinical programs
- Manage TMF content to ensure documents are filed and inspection-ready
- Ensure studies comply with FDA regulations, EU Directive, ICH guidelines, and NBI SOPs/policies
- Incorporate Risk Based Monitoring with Clinical Quality Assurance to assure subject safety and data integrity
- May support recruitment, training, management, and career development of subordinates
Requirements
- BS/BA + 8+ years clinical trial management (CRO/vendor management, budget scope monitoring, site monitoring) OR Master’s + 6+ years
- Expert knowledge of clinical drug development (ICH, GCP, FDA, EU)
- Strong knowledge of clinical operations and trial startup-through-close-out
- Strong trial management protocol/process knowledge across phases
- Excellent communication/presentation and computer/organizational skills
- Ability to lead multiple teams; strong leadership/mentoring and project management
Benefits (as stated)
- Annual bonus (target 30%), retirement plan with match, paid vacation/holidays/personal days, paid caregiver/parental and medical leave, and health benefits (medical, prescription drug, dental, vision).