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Sr. Business Systems Manager

BioCryst Pharmaceuticals, Inc.
Remote friendly (North Carolina, United States)
United States
IT

Role Summary

The Sr. Business Systems Manager is a technical lead and Oracle Fusion Cloud SME responsible for maximizing value, stability, and scalability of Oracle Fusion Cloud ERP, Procurement, HCM, SCM, and related modules in a regulated life sciences environment. The role provides hands-on techno-functional leadership and partners with MSPs, internal IT peers, and Finance, Procurement, Supply Chain, HR, and Quality stakeholders to deliver enhancements and lead technical workstreams.

Responsibilities

  • Configure, optimize, and enhance Oracle Fusion ERP, Procurement, HCM, SCM and Supply Planning modules.
  • Serve as the Oracle technical lead working with teams to build Oracle Fusion integrations with systems like Workday, Veeva, OneStream, and Concur using integration tools such as OIC and Boomi.
  • Manage quarterly updates, regression testing cycles, and change-control activities within a GxP-regulated environment.
  • Partner with IT, Finance, Supply Chain, HR, Quality and external partners to translate requirements into scalable Oracle solutions.
  • Lead complex, cross-functional technical projects, including integrations and system expansions.
  • Maintain documentation, SOPs, technical specifications, and audit readiness.
  • Govern Fusion security, role-based access, and segregation-of-duties standards.
  • Resolve incidents and service requests, conduct root-cause analysis, and implement long-term fixes.
  • Monitor system performance, SLAs, KPIs, and user adoption.
  • Provide technical leadership on Oracle integrations using OIC, OTBI, BI Publisher, and APIs.
  • Maintain proactive, consistent communication with cross-functional business stakeholders.
  • Ensure alignment between MSP support activities and business priorities.
  • Identify, assess, and prioritize opportunities to improve operational efficiency and business outcomes through technology.
  • Lead technical discussions translating business requirements into technical solutions
  • Co-ordinate with teams during UAT cycles to resolve issues
  • Support continuous improvement by assessing existing processes and recommending optimizations.
  • Manage and deliver small technology projects within the G&A portfolio.
  • Ensure strong vendor relationships and oversight of SLAs and support obligations.
  • Communicate technology updates and impacts affecting G&A business areas.
  • Create functional and design documentation, system standards, and procedures for G&A systems.
  • Follow project methodology, SDLC and change control processes to implement solutions
  • Ensure compliance with applicable laws, IT controls, regulatory guidelines, and data-governance standards.
  • Support audits, security assessments, and compliance activities related to G&A applications and data.
  • Support Audit requirements for SOX, CFR Part 11, and IT compliance.
  • Able to work flexibly across other technological platforms and cross-functional business areas when required.

Qualifications

  • Required: 8 years of experience in a related technical field, with at least 3 years of hands-on experience with Oracle Fusion Cloud, or an equivalent combination of education and experience.
  • Required: Experience designing and/or managing Oracle Fusion modules including Financials, SCM, Procurement, and HCM.
  • Preferred: Experience in GxP, SOX, and 21 CFR Part 11 environments strongly preferred.
  • Preferred: Strong preference for candidates with modern integration platforms experience such as Boomi, OTBI, security/role design, OIC, and BI Publisher.
  • Preferred: Experience in preparing documents for ITGC.
  • Preferred: Experience managing Veeva change control and deviation.
  • Preferred: Experience working in the life sciences industry.

Education

  • Bachelor's degree or equivalent in Business, Scientific or Technical discipline is required.