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Sr Bioinformatics Scientist

Twist Bioscience
October 3, 2026
Full-time
Remote friendly (South San Francisco, CA)
Worldwide
Other
Role: Senior Bioinformatics Scientist supporting R&D in DNA synthesis and protein solutions, developing computational algorithms and predictive models to analyze sequencing, DNA synthesis, and protein characterization data. Responsibilities: partner with experimental scientists to formulate hypotheses, analyze NGS and other datasets, develop workflows with Nextflow, evaluate methods, and communicate findings to guide product development and scientific understanding. Requirements: Ph.D. (3+ years), Master's (6+ years), or Bachelor's (8+ years) in bioinformatics, computational biology, or related; strong Python skills; experience with NGS, molecular biology, and algorithm development; expertise in statistics, experimental design, and reproducible workflow creation. Preferred: protein data analysis, machine learning, high-throughput data integration, cloud computing, established methods impacting product decisions. High-value specifics: focus on DNA synthesis, sequence analysis, protein characterization; supporting R&D innovation; collaborative cross-functional work; based in California with salary range $135K–$173K; hybrid work setup.