Sr Associate Scientist, Biology

Key Responsibilities:
- Design, develop, and execute bioanalytical assays for large molecules and ADC
- Perform ligand-binding assays (LBA) such as ELISA and MSD in different biological matrices to support PK studies
- Independently analyze and interpret experimental data; ensure data quality and integrity
- Independently troubleshoot assay performance issues and implement effective solutions
- Manage PK sample analysis workflows across multiple studies
- Collaborate with DMPK, biology, and project teams
- Prepare presentations and written reports
- Maintain accurate documentation
- Contribute to automation and workflow improvements
- Support broader discovery and screening activities

Required Qualifications:
- BS with 5+ years or MS with 3+ years in Pharmaceutical Science, Biochemistry, Biology or related discipline
- 2–3 years industry experience in PK bioanalysis, DMPK, or related field
- Hands-on experience independently supporting and executing in vivo PK studies for large molecules (e.g., monoclonal antibodies, peptides, biologics)
- Expertise in ligand-binding assays (ELISA, MSD, Gyrolab), including development, optimization, and troubleshooting
- Broad knowledge of PK bioanalytical assays, including ADA
- Ability to analyze/interpret PK data (4PL/5PL curve fitting, QC evaluation, trend analysis)
- PK/ADME knowledge for biologics (AUC, clearance, half-life, TMDD, nonlinear PK)
- Working knowledge of ADCs and bioanalytical challenges
- Proven ability to design experiments and troubleshoot independently
- Experience with biological matrices (serum, plasma, tissue)
- Ability to manage multiple studies and timelines
- Strong communication and presentation skills

Preferred Qualifications:
- Experience with LC-MS/MS
- Experience with in vitro high throughput screening technologies
- Familiarity with HTS (96/384/1536-well formats) and laboratory automation

Compensation/Benefits (if applicable):
- Salary range: $126,820.00 - $164,120.00; may be eligible for discretionary bonus, stock-based incentives, paid time off, and company-sponsored medical, dental, vision, and life insurance.

Application Instructions:
- For current employees and contractors, apply via the Internal Career Opportunities portal in Workday.