Spring 2026 Co-op: Quality Control

Role Summary

Spring 2026 Co-op: Quality Control at Prime Medicine, supporting the Analytical Development and QC team. The role provides hands-on experience with analytical techniques in gene and cell therapy, assisting with in-process, release, and stability testing for LNP-based drug products and prime editing component RNAs. You will learn regulatory requirements for phase-appropriate analytical testing and contribute to solving technical challenges related to the prime editing strategy. Note: local to the Boston/Cambridge area.

Responsibilities

• Support product development sample analyses, in-process, release and stability testing for:
  • LNP-based drug products
  • Prime editing component RNAs
• Participate in stability and reference standard programs, including protocol/report preparation, data compilation, and trend analysis
• Assist with sample management
• Conduct clean room lab environmental monitoring for GMP manufacturing suites
• Document and communicate experimental data in electronic notebooks per cGMP requirements
• Collaborate with teammates across the organization and program teams to support the product and method development, method qualification
• Contribute to laboratory functionality, safety, and QC process optimization
• Flexibility to support taking on new projects and troubleshooting as needs arise and priorities are dynamic
• Identify opportunities for assay optimization, process improvements, and automation

Qualifications

• Required: Currently enrolled in B.S./M.S. program in Biology, Biochemistry, Biotechnology, Bioengineering, Microbiology, Chemistry, Chemical Engineering, pharmacology, or a related field
• Required: Completion of foundational biology, biochemistry, microbiology, or chemistry coursework with a laboratory component
• Required: Ability to work both independently and collaboratively
• Required: Flexibility in taking on new projects and troubleshooting as needs arise
• Required: Self-motivated, detail-oriented with strong attention to problem-solving ability, and organizational skills
• Required: Excellent verbal and written communication skills
• Required: Eagerness to learn GLP/GMP practices and new analytical techniques
• Required: Comfortable engaging in cross-functional teamwork and communication
• Required: Ability to handle multiple projects in a fast-paced environment
• Preferred: Understanding of fundamental principles behind biological, microbiology, or chemical techniques, such as UV-vis, HPLC, UPLC, LC-MS, PCR/qPCR/ddPCR, potency assay, CFU identification and counting, etc.
• Preferred: Hands-on experience with biological or chemical analytical techniques, such as sample extraction, preparation, dilution, and analysis
• Preferred: Knowledge and/or experience in the field of gene and cell therapy, or willingness to learn
• Preferred: Previous intern or co-op experience in biotechnology industry