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Spring 2026 Co-op: Lung Biology

Prime Medicine, Inc.
Full-time
On-site
Cambridge, MA
Clinical Research and Development

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Role Summary

Spring 2026 Co-op: Lung Biology — Join the Lung Biology team to support preclinical and in vitro studies focused on developing prime editing therapies for Cystic Fibrosis, with emphasis on flow cytometry, tissue processing, and advanced cell culture systems.

Responsibilities

  • Keen interest in learning and performing the downstream analysis of in vivo studies, including tissue sample preparation, in vitro assays (PCR and Next-gen sequencing) and data analysis
  • Set up air–liquid cultures of human bronchial epithelial cells and maintain them throughout the experimental period
  • Plan and execute in vitro assays to evaluate gene editing activity in relevant primary cell models
  • Follow protocols, standard operating procedures, execute assigned tasks and maintain ELN. Share responsibility in lab reagent inventory and maintaining equipment
  • Work and collaborate cross-functionally with colleagues. Collect, analyze and present data in team meetings

Qualifications

  • Bachelors/Masters candidate in Biology-related major
  • Direct experience performing routine wet lab procedures and experiments
  • Hands on experience with sterile techniques and culturing of mammalian cell culture including primary cells
  • Experience with tissue sample preparation and immunostaining assays (flow cytometry, FACS, ICC/IHC) is a plus

Preferred Qualifications

  • Flow cytometry/FACS experience, including sample preparation and data analysis
  • In vitro molecular assays such as PCR/RT-qPCR
  • Gene editing technologies and viral and/or non-viral delivery
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