Small Scale Oligonucleotide Synthesis, Process Development Co-op (Spring 2026)
Wave Life Sciences
Full-time
Remote friendly (Lexington, MA)
United States
Operations
Want to see how your resume matches up to this job? A free trial of our JobsAI will help! With over 2,000 biopharma executives loving it, we think you will too! Try it now — JobsAI.
Role Summary
Small Scale Oligonucleotide Synthesis, Process Development Co-op (Spring 2026) at Wave Life Sciences, Lexington, MA. Gain exposure to oligonucleotide synthesis, formulation, purification, and analysis in a fast-paced, team-oriented biotech environment. Ideal for students pursuing chemistry, biology, biotechnology or related fields with strong organizational skills and attention to detail.
Responsibilities
- Prepare reagents and amidites for oligonucleotide synthesis
- Learn about solid phase synthesis and operate a Mermade192X synthesizer
- Purify oligonucleotides by preparative HPLC
- Analyze oligonucleotides by LC-MS, UV and pH
- Learn additional instrumentation including lyophilizers, speed vacs, nanodrop and UPLC
- Gain exposure to the use of an automated liquid handler for high throughput plate-based sample preparation
- Record and present data in an electronic laboratory notebook (ELN)
Qualifications
- Currently enrolled in an undergraduate or graduate science program in Chemistry, Biology, Biotechnology or related field
- Coursework in organic chemistry is required; biochemistry and analytical chemistry is a plus
- Understanding of laboratory best practices and safety protocols
- Attention to detail and well organized
- Laboratory experience with common laboratory operations including pipetting, weighing, and centrifugation preferred
- Enthusiasm for DNA/RNA therapeutic development