Senior Vice President, Clinical Development
Amylyx Pharmaceuticals
June 24, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
The Senior Vice President (SVP) of Clinical Development will provide strategic direction and technical leadership to the clinical development team, including clinical-regulatory development planning, clinical trial design, implementation and execution, clinical data analysis and management, and clinical competitive intelligence. This individual will also participate in business development evaluations, as applicable.
Responsibilities:
- Develop and implement comprehensive clinical development strategies aligned with business objectives.
- Lead and mentor a multidisciplinary team (medical directors, pharmacologists, and clinical development scientists).
- Oversee the design, execution, and analysis of clinical trials, ensuring adherence to timelines, budgets, and regulatory requirements.
- Collaborate with regulatory affairs on regulatory submission strategies and interactions with health authorities.
- Establish and maintain relationships with key opinion leaders, clinical investigators, and external partners.
- Develop and manage the clinical development budget.
Required Qualifications:
- MD or MD/PhD (specialization in Neurology or Endocrinology preferred).
- 15+ years in clinical development (biotech/pharma), with significant experience leading teams in rare disease drug development; successful BLA/NDA/MAA submission(s) and clinical/medical support of commercialization preferred.
- Proven leadership of cross-functional teams and ability to manage multiple projects in a fast-paced environment.
- In-depth knowledge of global regulatory requirements; experience with regulatory interactions and submissions.
- Excellent verbal and written communication skills.
Work Location:
- Remote; preference for candidates residing in New England who can regularly attend meetings in Cambridge, MA.
- Remote work requires appropriate work setup (privacy, reliable internet, phone, ability to video conference, etc.).
Compensation:
- $416,000 - $468,000 USD (estimated pay range).
Application instructions:
- Apply through the company website (click here to return).
Responsibilities:
- Develop and implement comprehensive clinical development strategies aligned with business objectives.
- Lead and mentor a multidisciplinary team (medical directors, pharmacologists, and clinical development scientists).
- Oversee the design, execution, and analysis of clinical trials, ensuring adherence to timelines, budgets, and regulatory requirements.
- Collaborate with regulatory affairs on regulatory submission strategies and interactions with health authorities.
- Establish and maintain relationships with key opinion leaders, clinical investigators, and external partners.
- Develop and manage the clinical development budget.
Required Qualifications:
- MD or MD/PhD (specialization in Neurology or Endocrinology preferred).
- 15+ years in clinical development (biotech/pharma), with significant experience leading teams in rare disease drug development; successful BLA/NDA/MAA submission(s) and clinical/medical support of commercialization preferred.
- Proven leadership of cross-functional teams and ability to manage multiple projects in a fast-paced environment.
- In-depth knowledge of global regulatory requirements; experience with regulatory interactions and submissions.
- Excellent verbal and written communication skills.
Work Location:
- Remote; preference for candidates residing in New England who can regularly attend meetings in Cambridge, MA.
- Remote work requires appropriate work setup (privacy, reliable internet, phone, ability to video conference, etc.).
Compensation:
- $416,000 - $468,000 USD (estimated pay range).
Application instructions:
- Apply through the company website (click here to return).