Senior Systems Engineer
Xeris Pharmaceuticals, Inc.
July 01, 2026
Remote friendly (Chicago, IL)
United States
IT
Essential Job Functions
- Own and advance the identity platform (Microsoft Entra ID, Azure AD Connect, and hybrid identity solutions).
- Design, implement, and manage endpoint management using Intune and Autopilot (application deployment, configuration, automation, patching).
- Configure and maintain enterprise applications using Entra ID, SAML SSO, and SCIM provisioning.
- Monitor, maintain, and optimize Windows servers (security patching and performance tuning).
- Implement and improve security best practices; conduct regular audits and remediate vulnerabilities.
- Lead or contribute to complex technical projects with cross-functional teams.
- Identify operational issues, propose solutions, and improve reliability and user experience.
- Manage and resolve advanced incidents/requests, including escalation when needed.
- Create and maintain documentation for configurations, standards, and procedures (risk assessment/validation support).
- Research and recommend innovative, automated approaches to systems administration.
Skills and Qualifications
- Bachelor’s in Computer Science/IT or equivalent experience.
- 3+ years supporting enterprise IT infrastructure.
- Strong Microsoft 365 and Azure experience (certifications a plus).
- Deep identity/access management knowledge (Entra ID, Azure AD Connect, SSO).
- Experience with Intune and Autopilot.
- Analytical problem-solving and clear communication to technical/non-technical stakeholders.
- Risk management experience aligned to security/compliance standards.
- Scripting in PowerShell, Microsoft Graph, KQL, or similar.
- Experience using Copilot/PowerPlatform or other AI tools to automate/enhance IT workflows.
- Innovation/continuous improvement mindset; strong ownership, teamwork, and project management.
Working Conditions
- Hybrid role (Chicago office); at least 3 days/week on site.
- Occasional evenings/weekends and periodic overnight travel.
Accessibility & Reasonable Accommodations
- For application accommodations, email recruiting@xerispharma.com with the job requisition number and requested assistance (no medical details).
- Own and advance the identity platform (Microsoft Entra ID, Azure AD Connect, and hybrid identity solutions).
- Design, implement, and manage endpoint management using Intune and Autopilot (application deployment, configuration, automation, patching).
- Configure and maintain enterprise applications using Entra ID, SAML SSO, and SCIM provisioning.
- Monitor, maintain, and optimize Windows servers (security patching and performance tuning).
- Implement and improve security best practices; conduct regular audits and remediate vulnerabilities.
- Lead or contribute to complex technical projects with cross-functional teams.
- Identify operational issues, propose solutions, and improve reliability and user experience.
- Manage and resolve advanced incidents/requests, including escalation when needed.
- Create and maintain documentation for configurations, standards, and procedures (risk assessment/validation support).
- Research and recommend innovative, automated approaches to systems administration.
Skills and Qualifications
- Bachelor’s in Computer Science/IT or equivalent experience.
- 3+ years supporting enterprise IT infrastructure.
- Strong Microsoft 365 and Azure experience (certifications a plus).
- Deep identity/access management knowledge (Entra ID, Azure AD Connect, SSO).
- Experience with Intune and Autopilot.
- Analytical problem-solving and clear communication to technical/non-technical stakeholders.
- Risk management experience aligned to security/compliance standards.
- Scripting in PowerShell, Microsoft Graph, KQL, or similar.
- Experience using Copilot/PowerPlatform or other AI tools to automate/enhance IT workflows.
- Innovation/continuous improvement mindset; strong ownership, teamwork, and project management.
Working Conditions
- Hybrid role (Chicago office); at least 3 days/week on site.
- Occasional evenings/weekends and periodic overnight travel.
Accessibility & Reasonable Accommodations
- For application accommodations, email recruiting@xerispharma.com with the job requisition number and requested assistance (no medical details).