Senior Systems Engineer
Xeris Pharmaceuticals, Inc.
September 02, 2026
Full-time
Remote friendly (Chicago, IL)
Worldwide
IT
Role: Senior IT Systems Engineer supporting core infrastructure for a biopharma environment, focusing on Microsoft 365, Azure, identity, and endpoint management. Responsibilities: design, implement, and optimize identity platforms (Microsoft Entra ID, Azure AD), manage endpoint solutions (Intune, Autopilot), ensure security, monitor Windows servers, lead technical projects, resolve complex incidents, and maintain documentation. Requirements: Bachelor's in Computer Science or related field; 3+ years supporting enterprise IT; strong expertise in Microsoft 365, Azure, identity management, PowerShell scripting; relevant certifications preferred. High-Value: experience supporting regulated biopharma environments; hybrid work model based in Chicago, with occasional travel; familiarity with security compliance, risk management, and automation tools; ability to communicate complex technical topics to varied stakeholders.