Senior Specialist, Quantitative Pharmacology and Pharmacometrics - Cardiometabolic and Ophthalmic Diseases
Merck
August 14, 2026
Remote friendly (Rahway, NJ)
United States
Clinical Research and Development
Responsibilities
- Contribute to model-based strategies (translational PK/PD, mechanistic models, POPPK/PD, clinical trial simulations) to inform and optimize drug discovery and development, including dose selection, clinical trial design, and go/no-go decisions.
- Represent QP2 across cardiometabolic and ophthalmology discovery, early, and late clinical development teams using quantitative approaches.
- Collaborate with internal functions and external vendors/partners on study design, protocol development, execution, reporting, and data interpretation.
Required Qualifications
- Ph.D. (or equivalent) OR PharmD (or equivalent) with 2+ years’ experience OR MS (or equivalent) with 4+ years’ experience in pharmaceutical drug development, regulatory agency work, or academia with increasing responsibility/independence.
- Background in biopharmaceutics/pharmaceutical sciences/pharmacometrcs/chemical/biomedical engineering or related field.
- Experience performing population PK and PK/PD analyses using standard pharmacometrics software (e.g., NONMEM, Monolix, Phoenix).
- Strong written/verbal communication, interdisciplinary collaboration, and problem scoping/planning.
Preferred Qualifications
- Knowledge of cardiometabolic and/or ophthalmology clinical drug development programs.
- Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.
- Understanding of biopharmaceutical and ADME properties of small molecules/biologics.
Required Skills
- Clinical study/clinical trial design, data modeling & visualization, pharmacokinetics & pharmacodynamics, interdisciplinary collaboration, and machine learning.
Application
- Apply at https://jobs.merck.com/us/en.
- Contribute to model-based strategies (translational PK/PD, mechanistic models, POPPK/PD, clinical trial simulations) to inform and optimize drug discovery and development, including dose selection, clinical trial design, and go/no-go decisions.
- Represent QP2 across cardiometabolic and ophthalmology discovery, early, and late clinical development teams using quantitative approaches.
- Collaborate with internal functions and external vendors/partners on study design, protocol development, execution, reporting, and data interpretation.
Required Qualifications
- Ph.D. (or equivalent) OR PharmD (or equivalent) with 2+ years’ experience OR MS (or equivalent) with 4+ years’ experience in pharmaceutical drug development, regulatory agency work, or academia with increasing responsibility/independence.
- Background in biopharmaceutics/pharmaceutical sciences/pharmacometrcs/chemical/biomedical engineering or related field.
- Experience performing population PK and PK/PD analyses using standard pharmacometrics software (e.g., NONMEM, Monolix, Phoenix).
- Strong written/verbal communication, interdisciplinary collaboration, and problem scoping/planning.
Preferred Qualifications
- Knowledge of cardiometabolic and/or ophthalmology clinical drug development programs.
- Skills in experimental design, mathematical problem solving, critical data analysis/interpretation, and statistics.
- Understanding of biopharmaceutical and ADME properties of small molecules/biologics.
Required Skills
- Clinical study/clinical trial design, data modeling & visualization, pharmacokinetics & pharmacodynamics, interdisciplinary collaboration, and machine learning.
Application
- Apply at https://jobs.merck.com/us/en.