Senior Software Engineer, Clinical Pharmacology and Pharmacometrics

Role Summary

Senior Software Engineer responsible for Pharmacometrics product suite development within the Clinical Pharmacology and Pharmacometrics (CPP) product team. The pharmacometrics product suite supports scientists working on PK/PD modeling methods. You will develop software solutions by understanding the information needs of Pharmacometrics scientists and collaborating with diverse product team members. Location: Cambridge, MA, and Lawrenceville, NJ.

Responsibilities

• Will be working as a part of the development team responsible for the overall technical deliverables of the various tools/applications/platforms used within Clinical Pharmacology and Pharmacometrics.
• Will work on enhancement requests within release schedules, interim workarounds, application life-cycle management and assist with new product evaluations and deployments.
• Will work with other internal IT (LDAP, AWS, Info Security, ITQM/ITQA, Scientific Computing Services, and storage teams), and external vendors (Metrum, Simulations Plus, PumasAI/JuliaHub, AWS, and other partners).
• Develops documentation, flowcharts, layouts, diagrams, charts, code comments, and clear code.
• Utilize available internal training opportunities.
• Collects, analyzes, and summarizes development and service issues.

Qualifications

• 3 - 5 years' experience as an applications developer in private, public, government or military environments - (large and small projects)
• 3 years' experience configuring and developing software leveraging modeling and simulation tools such as R, NONMEM, Monolix, Python, PsN, Pirana, SAS, JupyterHub.
• 2-3 years' experience working in a Linux environment
• 1-2 years' experience working with validated systems
• Good working experience building and enhancing custom shell and python scripts
• Experience with version control (SVN, GitHub)
• Familiarity with R package management strategies
• Integration experience

Skills

• Developer with programming skills in Python (primary) and R, integrating with API endpoints in AWS or Google cloud, knowledge of markdown languages such as Quarto/Typst
• Preferred: Experience working with LLM content ingestion, prompt engineering and content generation involving complex tables and images including special characters, headers, footers and merged columns to create new reports from a variety of source documents
• Understand all aspects of software development lifecycle
• Understand various SDLC methodologies (Agile, Scrum, Waterfall etc.)
• Familiarity with R/RStudio/RShiny
• Working System Administration knowledge for Linux
• NFS v4 File Systems, Access Control Lists (ACLs)
• Shell scripting
• Transferring functional to technical requirements
• Proficient in MS Office applications including Word, Excel, PowerPoint, and Outlook
• Knowledge of vector databases and graph RAG would be a plus
• Familiar with various IT and PM tools - JIRA, RTC etc.
• Agile methodologies
• ITIL certified
• Proficiency in one or more of the following areas UI/UX Design and Development, Cloud (AWS/Azure), work with SaaS / PaaS products