Senior Scientist, Translational Research (Oncology TRC)
Bristol Myers Squibb
August 13, 2026
Remote friendly (Cambridge, MA)
United States
Clinical Research and Development
Position Summary
Senior Scientist, Oncology Translational Research (Oncology TRC) — Cambridge, MA. Design scientific studies and deliver data impacting clinical decision-making. Advance oncology programs from candidate optimization through IND-enabling to Clinical Proof of Concept by exploring patient stratification, drug combination, and/or biomarker concepts.
Position Responsibilities
- Develop biomarker, pharmacodynamic, and target engagement assays
- Investigate MOA and sensitivity/resistance using current/new techniques
- Use flow cytometry and multiplexed assays for human blood biomarker development
- Perform quantitative biomarker assays (ELISA, MSD, Luminex, and others)
- Apply in vitro oncology models for drug combination and indication selection
- Use functional genomics tools (e.g., CRISPR, RNAi, ORF) for target/drug mechanism studies
- Coordinate with project teams and contract labs to design/oversee molecular, cellular, and/or in vivo studies
- Co-author non-clinical pharmacology reports and scientific publications
- Execute experiments independently; troubleshoot, interpret, and discuss data
- Communicate via email, meetings, and reports
Basic Qualifications
- Bachelor’s + 7+ years; or Master’s + 5+ years; or PhD/advanced life sciences + 2+ years (academic/industry)
Preferred Qualifications
- PhD + postdoc and/or 1–3 years industry; or BA/MA with 5–7 years industry in drug discovery/translational research
- Highly proficient in flow cytometry and human blood-based biomarker assay development
- Experience with biomarker-focused lab work (cell culture; protein/DNA/RNA analysis; MSD/ELISA, Luminex, RNAi, CRISPR, qPCR; primary cell isolation/culture/functional assays)
- Experience with patient-derived materials (organoid/tumoroid) valued
- Independent execution, accurate records, project prioritization, data interpretation, strong written/oral communication, problem-solving, flexibility
Benefits (explicitly listed)
- Health coverage (medical, pharmacy, dental, vision)
- Wellbeing support; 401(k); short-/long-term disability; life insurance and other protections
- Paid time off (flexible time off for US exempt employees or annual vacation for certain other employees)
Application instruction
If a role interests you but doesn’t perfectly match your resume, apply anyway.
Senior Scientist, Oncology Translational Research (Oncology TRC) — Cambridge, MA. Design scientific studies and deliver data impacting clinical decision-making. Advance oncology programs from candidate optimization through IND-enabling to Clinical Proof of Concept by exploring patient stratification, drug combination, and/or biomarker concepts.
Position Responsibilities
- Develop biomarker, pharmacodynamic, and target engagement assays
- Investigate MOA and sensitivity/resistance using current/new techniques
- Use flow cytometry and multiplexed assays for human blood biomarker development
- Perform quantitative biomarker assays (ELISA, MSD, Luminex, and others)
- Apply in vitro oncology models for drug combination and indication selection
- Use functional genomics tools (e.g., CRISPR, RNAi, ORF) for target/drug mechanism studies
- Coordinate with project teams and contract labs to design/oversee molecular, cellular, and/or in vivo studies
- Co-author non-clinical pharmacology reports and scientific publications
- Execute experiments independently; troubleshoot, interpret, and discuss data
- Communicate via email, meetings, and reports
Basic Qualifications
- Bachelor’s + 7+ years; or Master’s + 5+ years; or PhD/advanced life sciences + 2+ years (academic/industry)
Preferred Qualifications
- PhD + postdoc and/or 1–3 years industry; or BA/MA with 5–7 years industry in drug discovery/translational research
- Highly proficient in flow cytometry and human blood-based biomarker assay development
- Experience with biomarker-focused lab work (cell culture; protein/DNA/RNA analysis; MSD/ELISA, Luminex, RNAi, CRISPR, qPCR; primary cell isolation/culture/functional assays)
- Experience with patient-derived materials (organoid/tumoroid) valued
- Independent execution, accurate records, project prioritization, data interpretation, strong written/oral communication, problem-solving, flexibility
Benefits (explicitly listed)
- Health coverage (medical, pharmacy, dental, vision)
- Wellbeing support; 401(k); short-/long-term disability; life insurance and other protections
- Paid time off (flexible time off for US exempt employees or annual vacation for certain other employees)
Application instruction
If a role interests you but doesn’t perfectly match your resume, apply anyway.