Senior Scientist - Targeted Protein Degradation

Role: Senior Scientist in Targeted Protein Degradation within Amgen’s Induced Proximity Platform (IPP), focusing on developing E3 ligase-focused molecular glue screening and target discovery for therapeutics. Responsibilities: design and execute assays to validate molecular glue hits, characterize mechanisms, evaluate targets in disease-relevant models, collaborate on library development, and contribute to project goals. Requirements: Doctorate in Molecular Biology, Biochemistry, Chemical Biology, or related field with 1-2 years postdoctoral or industry experience; or Master’s degree with 4+ years relevant experience; or Bachelor’s degree with 6+ years relevant experience. Preferred skills include expertise in cell/molecular biology, high-throughput screening, CRISPR, mass spectrometry, and experience with induced proximity or protein degradation concepts. High-value specifics: focus on oncology, immunology, and cardiovascular biology; early-stage research, including molecular glue and targeted degradation mechanisms; cross-disciplinary collaboration with chemistry, proteomics, and pharmacology teams. Work setup and travel details are not specified.