Senior Scientist, Target Discovery & Biology - Functional Genomics

Role: Senior Scientist in Target Discovery & Biology focusing on functional genomics to identify and validate novel therapeutic targets across Amgen's pipeline in Oncology, Inflammation, and Rare Disease. Responsibilities: leverage in vitro and in vivo disease models, lead and support projects from target discovery through mechanism elucidation, and foster a collaborative, innovative research environment. Qualifications: PhD, MD, PharmD, or equivalent with relevant post-doc experience; or master's with 3+ years, bachelor's with 5+ years in Target Discovery & Biology. Preferred skills include molecular biology, cell engineering, complex co-culture models, large-scale genetic screens (e.g., CRISPR), and data-driven multi-omics approaches. Experience in applying functional genomics to diverse indications and a strong publication record are advantageous. High-Value: focus on complex biological systems, therapeutic areas of Oncology, Inflammation, Rare Disease, and early to mid-stage experimental research. Collaboration with cross-functional teams is implied; location is South San Francisco, with flexible work models. The role emphasizes innovation, scientific rigor, and impact on patient-centric drug discovery.