Senior Scientist, siRNA Analytical Development

Role: Senior Scientist in AbbVie's Biotherapeutic and Genetic Medicine department, focusing on developing analytical methods for siRNA and oligonucleotide therapeutics. Responsibilities: develop, optimize, and validate assays such as HPLC, LC-MS, and spectroscopy for characterization, purity, identity, and impurity profiling of siRNA/modifications; analyze data, ensure quality and compliance; support platform and project objectives through cross-functional collaboration; stay current with emerging analytical technologies. Requirements: BS/MS/PhD in Chemistry, Biochemistry, or related field; 0-4+ years (PhD) or 8-10+ years (MS), 10-12+ years (BS) relevant biotech/pharmaceutical experience; hands-on expertise in oligonucleotide analysis, chromatography, LC-MS, RNA chemistry, and modifications; strong troubleshooting, data analysis, and communication skills. HighValue: RNA-based therapeutics, oligonucleotides, siRNA platform, analytical characterization, support for genetic medicine programs, cross-functional partnerships. WorkSetup: not specified, but typically lab-based; no travel specified.