Senior Scientist - Protein Biochemist

Role: Senior Scientist – Protein Biochemist, focusing on designing and executing the generation of reagents for structural studies of drug targets via X-ray crystallography and cryo-EM. Responsibilities: collaborate with structural biologists to produce high-quality proteins, optimize purification protocols, develop methods, assess protein quality with biochemical techniques, support structural biology projects, and communicate findings effectively. Requirements: PhD, PharmD, MD, or equivalent with experience in molecular or structural biology; strong expertise in protein expression, purification (including challenging membrane proteins like GPCRs), and biophysical assessment methods; proficiency with chromatography systems (e.g., ÄKTA, HPLC). Preferred: experience with cryo-EM, X-ray crystallography, membrane proteins, and multiple expression systems; excellent troubleshooting and project management skills. High-Value: focus on challenging recombinant proteins for structural studies supporting drug discovery, particularly in oncology, inflammation, or rare diseases. Work setup: environment supporting collaboration with internal teams and CROs, with no specific travel or location details provided.