Senior Scientist or Principal Scientist, Targeted Proteomics

Role: Lead targeted proteomics scientist at a biotech focused on TPD (targeted protein degradation) therapeutic development, supporting preclinical and clinical programs. Responsibilities: develop and apply mass spectrometry assays (PRM, MRM) for pharmacodynamic profiling across biological matrices, collaborate with CRO partners for assay transfer and data quality oversight, and communicate findings to cross-functional teams. Experience: PhD in Biochemistry, Biology, Chemistry, or Chemical Biology with at least 2 years in industry-based targeted proteomics or BS/MS with 8+ years relevant experience; expertise in MS assay development, optimization, immunoaffinity enrichment, and data analysis (Skyline, DDA/DIA). HighValue: targeted proteomics, MS assay development, pharmacodynamics, preclinical and clinical biomarker support, CRO collaboration, scientific communication. WorkSetup: not specified, but implying collaboration with external partners and internal teams.