Senior Scientist - Neurobiology and Metabolism
Novo Nordisk
September 08, 2026
Full-time
Remote friendly (Lexington, MA)
Worldwide
Clinical Research and Development
Role: Senior Scientist leading neurobiology-driven drug discovery for obesity and cardiometabolic diseases within Novo Nordisk's Obesity Neurobiology US department. Responsibilities: spearhead target and project data packages, design and execute complex preclinical studies, and integrate mechanistic insights from human-relevant cellular systems, electrophysiology, receptor pharmacology, and multi-omics; coordinate cross-functional activities; guide external collaborations; mentor junior scientists; and contribute to assay/model development. Qualifications: Bachelor's (18+ years relevant experience), Master's (12+ years), or PhD (6+ years) in neuroscience, neurobiology, pharmacology, or related fields; extensive expertise in CNS physiology, receptor signaling, and neuroendocrine mechanisms; proven leadership in drug discovery or translational research; experience managing external CROs and academic collaborations. High-Value: focus on neurobiological mechanisms of energy balance, metabolic hormone signaling, GPCR pharmacology, and neural circuits; supporting small molecule and biologics programs; working across early discovery to preclinical development stages. Collaboration: reports to the Head of Obesity Neurobiology US, partnering with in vivo pharmacology, chemistry, computational biology, and translational teams. Work setup: not specified explicitly, but the role is based in Massachusetts. No travel expectations stated.