Senior Scientist, Multiomics Discovery

Role: Senior Scientist in Multiomics Discovery at Johnson & Johnson, focused on developing mechanistic insights from spatial omics-based phenotypic assays to support immunology, neuroscience, and oncology research. Responsibilities include designing genetic libraries for CRISPR and reporter systems, developing complex assay platforms such as high-content imaging and MPRA, engineering advanced cellular models including immune cells, organoids, and co-culture systems, and collaborating with computational teams for data analysis. The role emphasizes innovation in assay development, troubleshooting technical challenges, and expanding cellular and genomic methodologies. Requirements: PhD in relevant biological sciences, with 3+ years biotech or industry experience or equivalent postdoctoral/academic expertise; proven track record in genetic perturbation, high-impact publications, and complex model systems; expertise in massively parallel genetic screens, assay optimization, and data visualization; excellent communication skills. Preferred skills include proficiency in R/Python, experience with in vivo screens, histology, pathology, and next-generation sequencing. The position is based in Spring House, PA, with a focus on advancing spatial omics technologies and cellular screening platforms to enable discovery in complex disease biology.