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Senior Scientist, Immunology

Flagship Pioneering
September 04, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Clinical Research and Development
Role: Senior Scientist of Immunology specializing in T cell biology and in vivo CAR-T therapy development within a biotech-focused therapeutic discovery team. Responsibilities: lead and design complex in vitro assays (flow cytometry, cytotoxicity), develop and execute in vivo studies (humanized mice, NHPs), collaborate with CROs, troubleshoot protocols, analyze and communicate data, and contribute to strategic project planning. Qualifications: PhD in Immunology or related field with 5+ years of industry experience; expertise in flow cytometry, primary T cells, PBMCs, and mouse models; experience with humanized mice, NHPs, and in vivo CAR-T is strongly preferred; familiarity with nucleic acid modalities is a plus; highly motivated with strong organizational and collaborative skills. HighValue: CAR-T therapy, T cell biology, in vivo preclinical models (humanized mice, NHPs), in vitro immune assays, early to mid-stage therapeutic development, collaborative cross-functional environment, entrepreneurial setting.