Senior Scientist II, Rheumatology

Role: Senior Scientist II in Rheumatology within AbbVie's Discovery Immunology R&D, supporting preclinical programs for Rheumatoid Arthritis and Psoriatic Arthritis. Responsibilities: lead target validation, mechanism-of-action studies, and model development; drive in vivo and in vitro pharmacology, establish PK/PD relationships, and evaluate candidate efficacy using murine models; apply immunological techniques such as flow cytometry, gene expression, and cytokine analysis; generate and present scientific data; author technical reports and ensure compliance with safety and ethical standards. Requirements: Bachelor's with 12+ years, Master's with 10+ years, or PhD with 4+ years in immunology, inflammation biology, or related fields; proven expertise in preclinical disease models and pharmacology; strong communication and collaborative skills; industry experience preferred. HighValue: autoimmune diseases, inflammatory models, in vivo pharmacology, translational research, cross-functional collaboration. WorkSetup: not specified; likely in Cambridge, MA, with an emphasis on independent initiative and scientific innovation.