Senior Scientist II - Preclinical Primate Immunology

Role Summary

AbbVie's Immunology Discovery Research group is seeking a highly motivated in vivo and in vitro cellular immunologist to lead development of pharmacodynamic endpoints in non-human primate (NHP) preclinical pharmacology studies. This role involves testing and preclinically validating mechanistic and translational endpoints to support experimental medicine studies and to understand drug MOAs. You will work within a matrixed, collaborative team and influence the development strategy of high-value immunology programs.

Responsibilities

• Leverage deep non-human primate immunology expertise and current literature to advise project teams
• Communicate and coordinate study logistics within the existing team and across other stakeholders in Discovery Immunology.
• Coordinate with the team colony and study coordinator and supervisor regarding budget and colony maintenance while maintaining a high level of productivity
• Mentor and coach others while driving innovative science from the bench.
• Co-develop fit-for-purpose models to address specific program questions through networking with project relevant leads in the global organization.
• Directly develop translational immune-profiling assays.
• Establish translational rationale for utilizing primate models.
• Establish a tissue repository for rapid test article screening.
• Present results at project team meetings and internal/external science meetings.

Qualifications

• Bachelor’s Degree with typically 12+ years of experience, or Master’s Degree with 10+ years of experience, or PhD with 4+ years of experience in cellular immunology or related field
• Strong background in non-human primate immunology
• Hands-on experimentalist who understands advantages and challenges of in vivo and in vitro primate immunology
• Experience with multiparameter flow cytometry, especially with non-human primate samples
• Experience handling, processing, and isolating cells from primate tissues
• Familiarity with classical, mechanistic immunology models
• Experience with ELISA, MSD, Luminex, O-link and knowledge of cross reactivity limitations
• Demonstrate innovative thinking through publication or presentation of novel model and assay development, particularly in non-human primates
• Prior experience working in a highly matrixed environment is required