Senior Scientist II, Occupational & Environmental Toxicologist
AbbVie
10 hours ago
On-site
Irvine, CA
Clinical Research and Development
Onsite role based out of Irvine, CA.
Responsibilities:
- Critically evaluate literature and toxicology reports/summaries; use read-across and in silico tools to generate toxicology product risk assessments (e.g., extractables/leachables, HBELs/PDEs/OELs, environmental risk assessments, other contaminants).
- Collaborate with multi-functional teams to align on safety banding for implementation.
- Participate in external working groups to drive industry standards and monitor upcoming regulations.
- Provide guidance and mentorship to junior team members in GEO Tox and adjacent departments.
- Plan and monitor CRO studies for environmental assessments supporting regulatory filings.
- Plan and monitor CRO studies for worker safety/occupational safety and handling.
- Support evaluation/implementation of relevant new approach methodologies (NAM).
- Provide technical support for occupational health hazard categorizations and chemical registrations (GHS/CLP) and Safety Data Sheets (SDS).
Qualifications:
- Bachelor’s (toxicology or related) + typically 12 years experience OR Master’s + typically 10 years OR PhD + typically 4 years.
- Proven record of successfully evaluating safety risks.
- Excellent collaboration, multi-tasking, and communication; strong oral/written communication and attention to detail.
- Ability to work in a fast-paced environment and meet project deadlines.
Desired skills:
- Occupational Exposure Banding and/or performance-based exposure control limits; evaluating toxicity data for SDS.
- Risk assessment authoring.
- In-depth regulatory guidance knowledge (e.g., ICH Q3C/Q3D/Q3E, ICH M7, ISO-10993-X).
- Toxicity data mining in databases/literature.
- Software proficiency and in silico predictive tools (e.g., QSAR, OECD).
- Board certification preferred (not required).
Responsibilities:
- Critically evaluate literature and toxicology reports/summaries; use read-across and in silico tools to generate toxicology product risk assessments (e.g., extractables/leachables, HBELs/PDEs/OELs, environmental risk assessments, other contaminants).
- Collaborate with multi-functional teams to align on safety banding for implementation.
- Participate in external working groups to drive industry standards and monitor upcoming regulations.
- Provide guidance and mentorship to junior team members in GEO Tox and adjacent departments.
- Plan and monitor CRO studies for environmental assessments supporting regulatory filings.
- Plan and monitor CRO studies for worker safety/occupational safety and handling.
- Support evaluation/implementation of relevant new approach methodologies (NAM).
- Provide technical support for occupational health hazard categorizations and chemical registrations (GHS/CLP) and Safety Data Sheets (SDS).
Qualifications:
- Bachelor’s (toxicology or related) + typically 12 years experience OR Master’s + typically 10 years OR PhD + typically 4 years.
- Proven record of successfully evaluating safety risks.
- Excellent collaboration, multi-tasking, and communication; strong oral/written communication and attention to detail.
- Ability to work in a fast-paced environment and meet project deadlines.
Desired skills:
- Occupational Exposure Banding and/or performance-based exposure control limits; evaluating toxicity data for SDS.
- Risk assessment authoring.
- In-depth regulatory guidance knowledge (e.g., ICH Q3C/Q3D/Q3E, ICH M7, ISO-10993-X).
- Toxicity data mining in databases/literature.
- Software proficiency and in silico predictive tools (e.g., QSAR, OECD).
- Board certification preferred (not required).