Senior Scientist II β ADC Reaction Engineer
AbbVie
August 09, 2026
Remote friendly (North Chicago, IL)
United States
$109,500 - $208,500 USD yearly
Clinical Research and Development
Role Overview
- Develop robust manufacturing processes and advance innovative technologies across small molecules, ADCs, lipid nanoparticles, and toxins.
Key Responsibilities
- Develop scalable, commercial-ready manufacturing processes; support assets through all development phases.
- Participate in and/or lead teams to develop/characterize new small and large molecule assets; establish, communicate, and execute research plans.
- Develop lab/pilot processes; set strategies, timelines, and responsibilities in a matrixed environment.
- Solve challenging chemical/biochemical reactions and separations using kinetics, transport phenomena, and mathematical modeling.
- Apply process analytical tools and model-guided experimentation; build data/knowledge-driven models for scale-up and tech transfer.
- Author/review technical documents and support regulatory filings; collaborate cross-functionally and communicate recommendations.
- Author publications and present at scientific conferences.
Qualifications/Required Skills
- BS/MS/PhD in Chemical/Bio Engineering (or related); 12+ (BS), 10+ (MS), or 4+ (PhD) years relevant industry experience.
- Strong chemical engineering background.
- Demonstrated ability to model ADC kinetics/mechanisms.
- Drug linker and drug substance process design experience (tech transfer/scale-up).
- Flow chemistry reactor platform development (including for ADCs).
- Highly potent compound handling experience.
- Leadership of novel reactor configurations (e.g., photochemistry, electrochemistry, membrane reactors).
- Computational fluid dynamics expertise for reactor design and tech transfer.
- Strong oral/written communication and cross-functional leadership.
Benefits
- Paid time off (vacation/holidays/sick), medical/dental/vision insurance, 401(k); eligible for long-term incentive programs.
- Develop robust manufacturing processes and advance innovative technologies across small molecules, ADCs, lipid nanoparticles, and toxins.
Key Responsibilities
- Develop scalable, commercial-ready manufacturing processes; support assets through all development phases.
- Participate in and/or lead teams to develop/characterize new small and large molecule assets; establish, communicate, and execute research plans.
- Develop lab/pilot processes; set strategies, timelines, and responsibilities in a matrixed environment.
- Solve challenging chemical/biochemical reactions and separations using kinetics, transport phenomena, and mathematical modeling.
- Apply process analytical tools and model-guided experimentation; build data/knowledge-driven models for scale-up and tech transfer.
- Author/review technical documents and support regulatory filings; collaborate cross-functionally and communicate recommendations.
- Author publications and present at scientific conferences.
Qualifications/Required Skills
- BS/MS/PhD in Chemical/Bio Engineering (or related); 12+ (BS), 10+ (MS), or 4+ (PhD) years relevant industry experience.
- Strong chemical engineering background.
- Demonstrated ability to model ADC kinetics/mechanisms.
- Drug linker and drug substance process design experience (tech transfer/scale-up).
- Flow chemistry reactor platform development (including for ADCs).
- Highly potent compound handling experience.
- Leadership of novel reactor configurations (e.g., photochemistry, electrochemistry, membrane reactors).
- Computational fluid dynamics expertise for reactor design and tech transfer.
- Strong oral/written communication and cross-functional leadership.
Benefits
- Paid time off (vacation/holidays/sick), medical/dental/vision insurance, 401(k); eligible for long-term incentive programs.