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Senior Scientist I, Small Molecule and Peptide Bioanalysis

AbbVie
August 07, 2026
On-site
North Chicago, IL
$96,500 - $183,500 USD yearly
Clinical Research and Development
Purpose
- Join AbbVie’s Quantitative, Translational and ADME Science (QTAS) Department in the Non-regulated Bioanalysis Team (North Chicago). Develop and implement LC/MS-based bioanalysis to support preclinical pipeline studies; provide scientific leadership for custom methodologies for complex modalities; evaluate and implement novel technologies and methodologies.

Core Responsibilities
- Support method development and optimization for quantitative bioanalysis (including peptide extraction, separation, and quantification).
- Independently investigate, evaluate, and implement new analytical methodologies/technologies to meet challenging assay requirements while using resources effectively.
- Identify, troubleshoot, and quickly respond to instrument and assay issues.
- Operate/maintain LC/MS instruments; support pipeline-enabling preclinical studies and maintain accurate study documentation in electronic notebooks.
- Stay current with emerging analytical science literature.
- Mentor junior scientists.

Qualifications (Required/Preferred)
- PhD (0+ years), MS (8+ years), or BS (10+ years) in analytical chemistry or related field.
- In-depth LCMS methodology and quantitative science knowledge (focus on synthetic molecules).
- Hands-on experience with LC-MS/MS platforms and software; familiarity with automated sample preparation platforms.
- Plus: pharmacokinetics (experimental design and data analysis).
- Plus: regulated bioanalysis and/or CRO experience.
- Strong team collaboration; interdisciplinary interaction.
- Highly motivated; adaptable to shifting priorities.
- Excellent communication and presentation skills; ability to work independently and in teams.

Benefits (if explicitly stated)
- Paid time off (vacation, holidays, sick), medical/dental/vision insurance, 401(k).
- Eligible for short-term incentive programs.