Senior Scientist I / II, Drug Delivery Modeling & Simulation

Role Summary

As Senior Scientist I or II in AbbVie Drug Delivery Sciences, you will work as a key part of a multidisciplinary, cross-functional team to build capabilities for the delivery of biologics and small molecules and advance new products through early R&D. You will apply first-principles understanding to design, optimize, and analyze drug delivery platforms, utilizing quantitative models to predict and control drug release profiles.

Responsibilities

• Develop and apply mechanistic models for drug release kinetics from various sustained drug delivery platforms (e.g., in situ forming depots, implants, hydrogels).
• Employ first-principles approaches (e.g., diffusion, convection, chemical reaction theories) to solve complex transport problems relevant to drug delivery formulations.
• Design, execute, and analyze computational simulations using tools such as COMSOL Multiphysics or similar platforms.
• Collaborate with formulation and material scientists, and pharmacologists, to translate modeling results into experimental design and product development.
• Interpret experimental release data and integrate findings into enhanced models for predictive accuracy.
• Communicate findings through technical reports, publications, and presentations.

Qualifications

• PhD in Chemical Engineering
• Senior Scientist I: PhD with 0 - 4 years of relevant experience (industry, post-docs, or academia).
• Senior Scientist II: PhD with 4+ years of relevant industry experience.
• Strong foundation in mass transport phenomena (diffusion, dissolution, convection, degradation).
• Demonstrated expertise in mathematical modeling and simulation of controlled release mechanisms.
• Proficiency in relevant modeling and simulation software (COMSOL Multiphysics, Monte Carlo methods or equivalent).
• Excellent problem-solving, quantitative, and communication skills.
• Ability to work collaboratively in a multidisciplinary environment.
• Prior experience with drug delivery system design and evaluation is preferred.

Skills

• Mathematical modeling and simulation of drug delivery systems
• Computational tools: COMSOL Multiphysics or equivalent
• First-principles transport theory (diffusion, convection, reaction)
• Data interpretation and integration into predictive models
• Collaborative cross-functional communication

Education

• PhD in Chemical Engineering

Additional Requirements

• This is an on-site opportunity located in AbbVie's Irvine, CA location.