Senior Scientist – Functional Genomics

Role: Senior Scientist in Functional Genomics within Amgen's Target Discovery and Biology group, focusing on developing and applying genome engineering technologies to accelerate therapeutic target discovery across multiple disease areas, especially Oncology, Inflammation, and Rare Diseases. Responsibilities: design, engineer, produce, and optimize viral vectors (AAV, lentivirus) for genetic perturbation (CRISPR, overexpression) in vitro and in vivo; develop and implement genome engineering platforms; conduct experimental studies supporting target validation and mechanistic insights; collaborate across disciplines to translate emerging technologies into biological discoveries. Requirements: Ph.D. in Molecular Biology, Genetics, Virology, or related field with 1-2 years relevant experience, or equivalent with a Master’s or Bachelor’s degree plus experience; expertise in molecular biology, viral vector engineering (AAV, lentivirus), CRISPR technologies, and functional genomics; experience supporting in vivo/in vitro studies and genetic perturbation techniques. Preferred: demonstrated innovation in vector design, strong experimental and data analysis skills, and collaborative research success. HighValue: focus on genome engineering, viral vector platforms, therapeutic target discovery, and cross-functional collaboration. WorkSetup: Not specified, likely hybrid or lab-based; no travel explicitly mentioned.