Responsibilities:
- Conduct routine in-vitro ADME assays.
- Plan, perform, and report in vitro metabolism ADME studies for discovery and development stage compounds.
- Participate in experimental design; perform experiments; critically analyze, interpret, and report data to define next steps.
- Complete high-impact and high-throughput studies in a fast-paced environment while managing multiple projects to meet timelines.
- Establish new ADME assays and contribute to continuous improvement of existing assays.
- Guide junior scientists.
- Assist with data analysis and interpretation.
- Provide laboratory support (ordering, equipment calibration/validation) while adhering to the Quality System.
- Work with Project Managers to meet client requirements.
- Assist in running and maintaining robotic systems.
- Perform quality review of peer data; help consolidate assay control and validation criteria.
- Perform other duties as assigned.
Qualifications:
- PhD in a scientific relevant field (Ph.D. preferred) with experience in contract research organizations, pharmaceutical industries, or academia; OR Masterβs with 6+ years of experience.
- Equivalent education and experience acceptable.
- Industry/academic experience in DM/PK with a strong record of scientific achievement.
- Experience in drug discovery/development.
- Broad understanding of ADME, in vitro drug metabolism, and DDI.
- Knowledge of bioanalytical sciences including LC-MS/MS, GC-MS, biotransformation, and physical organic chemistry.
- Experience with cell-based or biochemical assays.
- Excellent oral and written communication; strong attention to detail.
- Proficiency with Microsoft Word and Outlook.
- Ability to manage time and work independently; communicate with peers and all levels of management.