Senior Scientist, Conjugation Process Development
Pfizer
September 09, 2026
Full-time
On-site
Bothell, WA
Operations
Role: Senior Scientist leading conjugation process development for antibody-drug conjugates (ADCs) targeting cancer within Pfizer's R&D. Objectives include designing and executing studies to advance ADC manufacturing processes, ensuring quality, and contributing to biotech innovation. Responsibilities encompass experimental design, data analysis, process troubleshooting, technology transfer, and contributing to regulatory documents and publications. The role involves mentoring team members and representing the group in multidisciplinary settings. Qualifications require a PhD with 0-3 years or a master's with 7-8 years of experience, along with expertise in bioconjugation, protein characterization (HPLC, IEF, CE-SDS), and working with cytotoxic molecules. Preferred skills include experience in GMP manufacturing, tangential flow filtration, chemical synthesis, and data analysis software such as JMP. High-value biopharma specifics include focus on ADCs for oncology, early to late-stage development, and process optimization. The position is on-premise, with no travel specified; it emphasizes scientific innovation within regulated bioconjugation and biologics development.