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Senior Scientist, Computational Biotherapeutics Engineering

Pfizer
September 08, 2026
Full-time
Remote friendly (Cambridge, MA)
Worldwide
Other
Role: Computational biotherapeutic discovery scientist focusing on AI/ML-driven protein modeling and design within Pfizer's BioMedicine Design department. Responsibilities: develop and implement advanced AI workflows for protein structure and sequence modeling, collaborate on antibody developability and biotherapeutic optimization, analyze large biological datasets, and support discovery teams with model insights. Qualifications: PhD in biochemistry, computational biology, or related field with up to 3 years' experience, or equivalent industry experience; proficiency in Python, deep learning frameworks (PyTorch), and bioinformatics; proven track record in AI/ML applications for protein design, with publications or impactful contributions. HighValue: AI/ML protein modeling, generative design, antibody engineering, biotherapeutic discovery, use of models like AlphaFold, RFdiffusion, structural prediction, cloud/HPC computing, interdisciplinary collaboration. WorkSetup: Hybrid location with 2.5 onsite days/week, U.S. work authorization required, no visa sponsorship.