Senior Scientist, Computational Biology

Role: Computational biologist specializing in genome editing technologies, focusing on off-target discovery assays and NGS data analysis. Responsibilities: develop, execute, troubleshoot cloud-based NGS pipelines; collaborate with experimental scientists to interpret multi-omics data; present findings to interdisciplinary teams; support gene writing research in a fast-paced environment. Requirements: PhD with 5+ years or MS with 10+ years or BS with 12+ years in computational biology or related field; hands-on expertise in genome editing assays (WGS, GUIDE-seq, Digenome-seq), cloud computing (AWS), workflow tools (Nextflow, Dagster), and AI tools; strong programming and data interpretation skills. Preferred: experience in gene therapy, genomic safety, or related biopharma areas. HighValue: focus on gene writing systems, genome editing assay development, cloud-based NGS pipelines, interdisciplinary collaboration, hybrid work in Somerville, MA, with some onsite presence.