Senior Scientist-Clinical Bioanalysis

Role: Senior Scientist/Manager, Clinical Bioanalysis, leading development and qualification of assays for immune-mediated disease programs, supporting clinical pharmacology and translational biomarker analysis. Responsibilities: collaborate across research, clinical development, and external labs; develop and validate bioanalytical assays for target engagement, cytokines, chemokines, soluble receptors, immune cell markers; support DMPK activities including PK, ADA, PD; ensure sample handling and assay transfer compliance; manage CRO partnerships and multiple projects. Requirements: MS or PhD in Analytical Biochemistry, Immunology, Cell Biology, or related field; 2+ years (PhD) or 4+ years (MS) in biopharma/CRO supporting translational/clinical bioanalysis; experience with ligand-binding assays, multiplex cytokine panels, flow cytometry, cell-based assays; background in immune biomarkers and DMPK bioanalysis preferred. HighValue: immune-mediated diseases, biologics, translational biomarkers, regulatory compliance, clinical bioanalytical platforms, collaboration with external labs, Lexington MA onsite, no travel specified.