Senior Scientist, Chip and Surface Chemistry

Role Summary

Senior Scientist, Chip and Surface Chemistry responsible for enhancing the functionality and reliability of the platform’s flow cell and surface chemistry components. The candidate will apply expertise in surface chemistry and process development across assay development, metrology, data analysis, and system integration.

Responsibilities

• Collaborate with lead scientists and engineers to develop and validate processes related to nanofabrication, surface chemistry, and flow cell assembly.
• Design and implement analytical and functional methodologies to characterize and assess the effectiveness of chip patterning, surface chemistry, and flow cell assembly processes.
• Test and implement assay, flow cell, and surface chemistry improvements on Nautilus’ proteomics platform.
• Apply statistical process control methods to establish and maintain control and specification limits.
• Experience with DNA origami design, fabrication, and integration in biosensors is a plus.

Qualifications

• PhD + 6 year's experience or BS/MS + 12 years
• Degree in Chemical Engineering, Materials Science, Analytical Chemistry, Surface Science, Polymer Chemistry, or a related scientific or engineering discipline preferred.
• Prior experience supporting a commercial product line with a critical surface chemistry component is essential.
• In-depth knowledge of metal oxide passivation strategies suitable for single-molecule optical assays is required.
• Strong expertise in bioconjugation and surface passivation techniques including quantitative analysis of conjugation/passivation efficiency.
• Familiarity with strategies and methods for device qualification, functional testing, and failure analysis.
• Expert knowledge of surface characterization techniques such as ellipsometry, XPS, AFM, fluorescence microscopy, and optical single-molecule assays.
• Basic knowledge of molecular biology and biochemistry is desirable.
• Excellent presentation, verbal, and written communication skills.