Senior Scientist, Biology-Discovery, Neuroscience Biomarkers, Mass Spectrometry
Merck
October 1, 2026
Full-time
Remote friendly (West Point, PA)
Worldwide
Clinical Research and Development
Role: Senior Scientist in Discovery Neuroscience focusing on biomarker discovery and validation for neurodegenerative diseases using mass spectrometry-based assays. Responsibilities include developing and applying LC-MS techniques (DDA, DIA proteomics, LC-MS/MS) for preclinical models and human biospecimens, supporting target identification and translational research, and collaborating with multidisciplinary teams to develop fluid biomarkers for clinical translation. Tasks also involve assay transfer, external collaboration, and bioinformatics analysis using tools like Skyline, MaxQuant, and Spectronaut. Requirements: PhD in Analytical Chemistry or related field with at least four years postdoctoral/industry experience; expertise in omics (metabolomics, lipidomics, proteomics), mass spectrometry, assay development, data processing, and bioinformatics; experience with neurodegenerative disease research preferred. HighValue: neurodegeneration, biomarker discovery, mass spectrometry, preclinical models, human biospecimens, translational biomarker assays, assay transfer, external collaborations. WorkSetup: not specified; travel not required.