Senior Scientist, Antibody Repertoire Sequencing & Discovery

Role: Senior Scientist in Molecular Core focused on antibody repertoire sequencing (RepSeq) for therapeutic antibody discovery within AbbVie's Biotherapeutics and Genetics Medicine department. Responsibilities: leading RepSeq technology development, optimizing sequencing platforms (including 10X, Illumina, PacBio), collaborating with computational scientists on repertoire analysis and machine learning applications, and managing data generation/documentation for antibody discovery projects. Requirements: PhD or MS in immunology, molecular biology, bioinformatics, with 8-12+ years of relevant experience; expertise in immunoglobulin genetics, antibody biology, NGS technologies, molecular biology techniques, and computational analysis; proficiency with analysis software and AI/ML tools. Preferred: experience with non-human immunogenetics, large DNA/protein dataset analysis, in vitro antibody library repertoire sequencing, mammalian cell culture, and immunoassays. High-Value: focus on immunology and antibody discovery, utilizing advanced sequencing and bioinformatics tools, supporting immuno-oncology, neurology, and immunology therapeutic programs. Work setup: not explicitly stated, likely a laboratory-focused role at ABC Worcester, MA.