What Youโll Do
- Perform routine in-vitro ADME assays.
- Plan, perform, and report in vitro metabolism ADME studies for discovery and development-stage compounds.
- Participate in experimental design; perform experiments and critically analyze, interpret, and report data to design next steps.
- Complete high-impact and high-throughput studies in a fast-paced environment while managing multiple projects to meet timelines.
- Establish new ADME assays and contribute to continuous improvement of existing assays.
- Guide junior scientists in the department.
- Assist in data analysis and interpretation.
- Provide laboratory support (ordering, equipment calibration/validation) and adhere to the Quality System.
- Work with Project Managers to meet client requirements.
- Assist in running and maintaining robotic systems supporting processes.
- Perform quality review of peer data and assist with consolidating assay control and validation criteria.
Who You Are (Qualifications)
- PhD in a relevant scientific field (PhD preferred) with experience in contract research organizations, pharmaceutical industries, or academia; or Masterโs with 6+ yearsโ experience (equivalent education/experience may substitute).
- Industry/academic experience in DM/PK with a record of scientific achievement.
- Experience in drug discovery/development.
- Broad understanding of ADME, in vitro drug metabolism, and DDI.
- Knowledge of bioanalytical sciences (LC-MS/MS, GC-MS, biotransformation, physical organic chemistry).
- Experienced in cell-based or biochemical assays.
- Excellent oral/written communication; strong attention to detail.
- Knowledge/proficiency with Microsoft Word and Outlook; ability to manage time and work independently.